Monitoring disease activity in multiple sclerosis using serum neurofilament light protein

Conclusions: Serum and CSF NFL levels were highly correlated, indicating that blood sampling can replace CSF taps for this particular marker. Disease activity and DMT had similar effects on serum and CSF NFL concentrations. Repeated NFL determinations in peripheral blood for detecting axonal damage may represent new possibilities in MS monitoring.

http://www.neurology.org/cgi/content/short/89/22/2230?rss=1

Source: Neurology - November 27, 2017 Category: Neurology Authors: Novakova, L., Zetterberg, H., Sundström, P., Axelsson, M., Khademi, M., Gunnarsson, M., Malmeström, C., Svenningsson, A., Olsson, T., Piehl, F., Blennow, K., Lycke, J. Tags: Cerebrospinal Fluid, Multiple sclerosis ARTICLE Source Type: research

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