Cross-linking effect on dentin bond strength and MMPs activity

Currently, adhesive dental restorations are an essential part in everyday dental practice [1]. However, despite evolution of adhesive protocols, the hybrid layer (HL) remains the weakest point of resin –composite restorations. The structure of this connecting layer is responsible for the retention of the resin restorations. However, it is also the most vulnerable area of the adhesive-resin bond [2]. Previous in vitro and in vivo studies revealed that degradation of resin dentin bonds over time i s caused by hydrolytic breakdown of the resin or of dentinal collagen fibrils [3,4], identifying the important contribution of host derived proteinases in the deterioration of the hybrid layer over time [5–8].
Source: Dental Materials - Category: Materials Science Authors: Source Type: research