Matrix metalloproteinase-2 knockout prevents angiotensin II-induced vascular injury

ConclusionsMmp2 knockout impaired Ang II-induced vascular injury but not BP elevation. BM transplantation revealed a role for immune cells in Ang II-induced BP elevation, and for both vascular and immune cell MMP2 in Ang II-induced endothelial dysfunction.

https://academic.oup.com/cardiovascres/article/113/14/1753/3980138?rss=1

Source: Cardiovascular Research - July 20, 2017 Category: Cardiology Source Type: research