Kidney failure: Symptoms of condition that killed The Partridge Family star David Cassidy
KIDNEY FAILURE is caused by the organs not functioning properly, and an estimated 13,000 people die from chronic kidney disease in the UK every year. David Cassidy died from suspected kidney failure this week.
Authors: Wang H, Li Z, Guo X, Chen Y, Chen S, Tian Y, Sun Y Abstract BACKGROUND: Despite current interest in the unfavorable impact of nontraditional lipid profiles on cardiovascular disease, information regarding its relations to reduced glomerular filtration rate (GFR) in H-type hypertension population has not been systemically elucidated. METHODS: Analyses were based upon a cross-sectional study of 3259 participants with H-type hypertension who underwent assessment of biochemical, anthropometric, and blood pressure values. Reduced GFR was considered if meeting estimated GFR
We examined the association of pro-ENK with eGFR and UAE as a markers of CKD. METHODS: We included 4,375 subjects of the Prevention of Renal and Vascular End-Stage Disease (PREVEND) study. CKDeGFR was defined as development of eGFR 30 mg/24h. RESULTS: Baseline median pro-ENK was 52.2 (IQR: 44.9-60.5) pmol/L. After a median follow-up of 8.4 (IQR: 7.9-8.9) years, 183 subjects developed CKDeGFR and 371 developed CKDUAE. The association of pro-ENK with CKDeGFR was modified by sex (Pinteraction
ConclusionLow levels of parathyroid hormone before transplantation were associated with increased risk of post-transplant vascular events both in patients with and without pre-transplant parathyroidectomy. Any conclusions on causal or direct effect of PTH on outcome cannot be drawn from this observational study.
FRIDAY, Feb. 23, 2018 -- Chronic kidney disease may affect brain function in children and teens, especially those on dialysis, researchers say. Results of their study review suggest academic assistance may be needed in specific areas, including...
Conclusions In this case-control, survey-based study, the prevalence of nephrolithiasis was 2 times higher in patients with CLD.
AbstractMany cardiovascular diseases present renin –angiotensin–aldosterone system (RAAS) hyperactivity as an important pathophysiological mechanism to be target in the therapeutic approaches. Moreover, arterial stiffness is currently considered as a new independent risk factor for cardiovascular disease in different clinical conditions, includi ng hypertension and chronic kidney disease. In fact, excessive stimulation of angiotensin type 1 (AT1) receptors, as well as mineralocorticoid receptors, results in cellular growth, oxidative stress and vascular inflammation, which may lead to arterial stiffness and acc...
There is a large and growing burden of diabetes globally. In 2013, 382 million people had diabetes and this number has been projected to increase to 592 million by 2035 . With increasing life expectancy and prevalence of type 2 diabetes, complications and deaths attributable to diabetes will also increase, especially if there is no concomitant improvement in the health system for its early management . Chronic kidney disease (CKD) is a common complication in people with type 2 diabetes  and may in some cases progress to end-stage renal disease, which requires dialysis and/or kidney transplant which are associated ...
ConclusionOur results prompt another mechanism of anti-fibrotic renal protection of renalase, which may be partly associated with inhibiting oxidative stress. These data provided another theoretical basis that supplementation with exogenous renalase may be a promising strategy for slowing or halting the progression of CKD.
Conclusion: CKD is frequent at PAH diagnosis and is independently associated with increased mortality. Right heart failure may induce renal hypoperfusion and congestion, and is associated with eGFR decrease.Am J Nephrol 2018;47:134 –143