[Correspondence] Pembrolizumab is effective for drug-resistant gestational trophoblastic neoplasia

Gestational trophoblastic disease represents a spectrum of pregnancy related disorders, ranging from pre-malignant hydatidiform mole to malignant tumours, collectively referred to as gestational trophoblastic neoplasia. Gestational trophoblastic neoplasia includes malignant invasive mole, choriocarcinoma, and rare placental site trophoblastic and epithelioid trophoblastic tumours.1 Globally, approximately 18  000 women are diagnosed with gestational trophoblastic neoplasia annually, most of whom are cured with chemotherapy guided by the sensitive disease response biomarker, human chorionic gonadotropin.

Source: LANCET - November 24, 2017 Category: General Medicine Authors: Ehsan Ghorani, Baljeet Kaur, Rosemary A Fisher, Dee Short, Ulrika Joneborg, Joseph W Carlson, Ayse Akarca, Teresa Marafioti, Sergio A Quezada, Naveed Sarwar, Michael J Seckl Tags: Correspondence Source Type: research