Efficacy of continuous blood purification on patients with severe acute pancreatitis associated acute respiratory distress syndrome

Source: Respirology - Category: Respiratory Medicine Tags: Critical Care Medicine Source Type: research

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Authors: Yu JH, Lim JW, Kim H Abstract Pancreatitis is a disease for which there are numerous etiologies but no effective treatments. Although the expression of the pancreatitis-associated protein-1 (PAP-1) serves as a marker for the disease, its biological function is unknown. The present study was carried out to determine if PAP-1 performs a protective role against oxidative stress-induced pancreatic cell death. For this purpose, we used cerulein-stimulated pancreatic acinar AR42J cells as an experimental model of acute pancreatitis. First, we demonstrated that PAP-1 gene expression is increased by cerulein in a ...
Source: Journal of Physiology and Pharmacology - Category: Drugs & Pharmacology Tags: J Physiol Pharmacol Source Type: research
Authors: Buzcu H, Ozbeyli D, Yuksel M, Cilingir Kaya OT, Kasimay Cakir O Abstract Nesfatin-1, a recently discovered peptide, was shown to have anti-inflammatory effects. Acute pancreatitis (AP) is a life-threatening condition caused by various reasons. Although the etiology of AP is well-known, its pathogenesis is not clear. The aim of this study is to investigate the possible anti-inflammatory role of nesfatin-1 and its probable protective underlying mechanisms in an acute pancreatitis model. Caerulein was applied intraperitoneally to induce acute pancreatitis in Sprague-Dawley female rats. Nesfatin-1 was administ...
Source: Journal of Physiology and Pharmacology - Category: Drugs & Pharmacology Tags: J Physiol Pharmacol Source Type: research
Publication date: April 2020Source: Cancer Epidemiology, Volume 65Author(s): Ahmed Arafa, Ehab S. Eshak, Tarek A. Abdel Rahman, Manal M. AnwarAbstractBackgroundA growing body of evidence has suggested an association between Hepatitis C virus (HCV) infection and risk of pancreatic cancer (PAC). Herein, we conducted a meta-analysis of available evidence to explore this association.MethodsWe systematically retrieved studies that investigated the association between HCV infection and risk of PAC. Pooled odds ratio (OR) with corresponding 95 % confidence interval (CI) of PAC for patients with HCV infection was calculated using ...
Source: Cancer Epidemiology - Category: Cancer & Oncology Source Type: research
ConclusionsMesna mitigates AP by alleviating pancreatic oxidative stress damage and inhibiting inflammation.
Source: Digestive Diseases and Sciences - Category: Gastroenterology Source Type: research
Publication date: Available online 20 February 2020Source: Clinics and Research in Hepatology and GastroenterologyAuthor(s): Mateus Pereira Funari, Igor Braga Ribeiro, Diogo Turiani Hourneaux de Moura, Wanderley Marques Bernardo, Vitor Ottoboni Brunaldi, Daniel Tavares Rezende, Ricardo Hannum Resende, Michele Oliveira de Marco, Tomazo Antonio Prince Franzini, Eduardo Guimarães Hourneaux de MouraSummaryBackgroundBiliary sphincterotomy is an invasive method that allows access to the bile ducts, however, this procedure is not exempt of complications. Studies in the literature indicate that the mode of electric current ...
Source: Clinics and Research in Hepatology and Gastroenterology - Category: Gastroenterology Source Type: research
ConclusionsThe minor duodenal papilla and aging do not likely play an important role in the occurrence of dorsal duct obliteration. Although frequency of obliterated ventral duct was low in our population, physicians, including gastroenterologists and endoscopists, as well as islet transplantation researchers should be aware of this possibility.
Source: Digestive Diseases and Sciences - Category: Gastroenterology Source Type: research
BackgroundCurrent magnetic resonance imaging (MRI) of pancreatic disease is qualitative in nature. Quantitative imaging offers several advantages, including increased reproducibility and sensitivity to detect mild or diffuse disease. The role of multiparametric mapping MRI in characterizing various tissue types in pancreatic disease such as chronic pancreatitis (CP) and pancreatic ductal adenocarcinoma (PDAC) has rarely been evaluated.PurposeTo evaluate the feasibility of multiparametric mapping [T1, T2, and apparent diffusion coefficient (ADC)] in defining tissue characteristics that occur in CP and PDAC to improve diseas...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
Conclusions Initial experience with the EndoRotor suggests that this device can safely, rapidly, and effectively remove necrotic tissue in patients with (infected) walled-off pancreatic necrosis. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text
Source: Endoscopy International Open - Category: Gastroenterology Authors: Tags: Original article Source Type: research
To evaluate the clinical and imaging features and endovascular management of arterial pseudoaneurysms (PSA) in the setting of pancreatitis.
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Scientific e-Poster Source Type: research
Publication date: Available online 19 February 2020Source: European Journal of RadiologyAuthor(s): Mahya Faghih, Vikesh K. Singh, Mashayekhi R, Parekh VS, Michael A. Jacobs, Atif Zaheer
Source: European Journal of Radiology - Category: Radiology Source Type: research
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