Allergen immunotherapy might reduce basophil response in house dust mite allergic patients

Source: Respirology - Category: Respiratory Medicine Tags: Clinical Allergy & Immunology / Paediatric Lung Disease Source Type: research

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Abstract Metals are essential components in all forms of life required for the function of nearly half of all enzymes and are critically involved in virtually all fundamental biological processes. Especially, the transition metals iron (Fe), zinc (Zn), manganese (Mn), nickel (Ni), copper (Cu) and cobalt (Co) are crucial micronutrients known to play vital roles in metabolism as well due to their unique redox properties. Metals carry out three major functions within metalloproteins: to provide structural support, to serve as enzymatic cofactors, and to mediate electron transportation. Metal ions are also involved in...
Source: Advances in Immunology - Category: Allergy & Immunology Authors: Tags: Adv Immunol Source Type: research
CONCLUSIONS: Severe SE, not outcomes, was the most decisive attribute determining future HCRCT participation. Particular attention should be paid to providing clear information, in particular on severe SE, to potential participants. Immunotherapy would appear to be the best HCRCT candidate for both PLWH and physicians. However, if the risk of cancer could be avoided, gene therapy would become the preferred strategy for the latter and the second choice for the former. PMID: 32077248 [PubMed - in process]
Source: Journal of the International AIDS Society - Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research
The objectives were to examine physician and patient perceptions of seasonal allergy symptoms ...
Source: Allergy, Asthma and Clinical Immunology - Category: Allergy & Immunology Authors: Tags: Research Source Type: research
AbstractPurpose of ReviewPrecision medicine (PM) represents a new paradigm in disease diagnosis, prevention, and treatment. The PM approach focuses on the characterization of different phenotypes and pathogenic pathways in order to allow the selection of specific biomarkers that will be useful in disease management. Rhinitis is a highly prevalent and heterogeneous disease, both in terms of underlying endotypes and clinical presentations. Therefore, to apply the PM principles to the various rhinitis subtypes rise as a meaningful strategy to improve evaluation and treatment.Recent FindingsThe technology of recombinant allerg...
Source: Current Treatment Options in Allergy - Category: Allergy & Immunology Source Type: research
Oral Immunotherapy for peanut allergy (PACE): a systematic review and meta-analysis of efficacy and safety.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: From the Pages of AllergyWatch Source Type: research
Conditions:   Hymenoptera Venom Allergy;   Antihypertensive Treatment Intervention:   Drug: Insect Venom Sponsor:   Medical University of Graz Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Birch Pollen Allergy Intervention:   Biological: DM-101 Sponsor:   Desentum Oy Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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