Risk stratification for the development of chronic pulmonary aspergillosis in patients with mycobacterium avium complex lung disease

Source: Respirology - Category: Respiratory Medicine Tags: Respiratory Infections (non ‐tuberculosis) 1 Source Type: research

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Publication date: Available online 22 January 2020Source: Journal de Mycologie MédicaleAuthor(s): Arghadip Samaddar, Anuradha Sharma, Twishi ShrimaliAbstractAcrophialophora fusispora is a soil-borne fungus rarely implicated in human infections. Here, we report a case of pulmonary infection due to A. fusispora in a 59-year-old male who presented with productive cough and gradually progressive dyspnoea for 20 days. He had a past history of pulmonary tuberculosis and was a known case of chronic obstructive pulmonary disease for past five years. He was diagnosed with mixed connective tissue disease and had been receivin...
Source: Journal of Medical Mycology - Category: Biology Source Type: research
AbstractBackgroundAllergic bronchopulmonary aspergillosis (ABPA) is an allergic pulmonary disease caused by a hypersensitivity reaction to Aspergillus colony in the airways. Due to the diversity of disease manifestations and physicians ’ incomplete knowledge of ABPA, patients with ABPA are often misdiagnosed and given poor prognosis.ObjectivesTo investigate the clinical characteristics, treatment and prognosis status among patients with ABPA.MethodsWe retrospectively analyzed 75 patients diagnosed as ABPA in Zhongshan Hospital, Fudan University between October 2008 and June 2018.ResultsAmong 75 patients, 28% had asth...
Source: The Clinical Respiratory Journal - Category: Respiratory Medicine Authors: Tags: ORIGINAL ARTICLE Source Type: research
Limited data are available regarding the prognostic factors for patients with nontuberculous mycobacterial pulmonary disease (NTM-PD). We investigated the prognostic factors associated with long-term mortality in NTM-PD patients after adjusting for individual confounders, including aetiological organism and radiological form. A total of 1445 patients with treatment-naïve NTM-PD who were newly diagnosed between July 1997 and December 2013 were included. The aetiological organisms were as follows: Mycobacterium avium (n=655), M. intracellulare (n=487), M. abscessus (n=129) and M. massiliense (n=174). The factors associated...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Respiratory infections and tuberculosis Original Articles: Lung infection Source Type: research
Conference abstracts
Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news
ConclusionsThe diagnosis and management of IRIS in the lung in non-HIV patients should be investigated further, especially in the era of anti-TNF treatment.
Source: Respiratory Investigation - Category: Respiratory Medicine Source Type: research
Conclusion: Patient with ABPA frequently received empiric ATT as smear –ve TB in high TB burden country. This results in over diagnosis of TB and unnecessary use of global resource. Moreover dealy in diagnosis leads to long term complications. Awareness regarding ABPA is required in high TB burden countries.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Tuberculosis Source Type: research
This study is to analyzed Cumulative incidence and associated risk factor of chronic pulmonary infection after lung resection surgery for lung cancerWe retrospectively analyze cumulative incidence and associated risk factor of chronic pulmonary infection for total of 3491 patients who was operated lung resection surgery for lung cancer from January 2010 to December 2014Of the 3,491 patients who underwent surgery for lung cancer, 123 developed chronic pulmonary infection (29 pulmonary tuberculosis, 47 non-tuberculous mycobacterial lung disease, 56 chronic pulmonary aspergillosis, 1 pulmonary actinomycosis). The cumulative i...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Lung cancer Source Type: research
Background: Chronic pulmonary aspergillosis (CPA) is a chronic progressive infectious disease that occurs frequently in patients with underlying pulmonary disease. Only a few reports have studied the clinical characteristics and prognosis of CPA.Aims and Objectives: We aimed to investigate the clinical characteristics of CPA patients and their prognosis. We retrospectively analyzed patients diagnosed as having CPA between 2014 and 2017 in our hospital.Results: We enrolled 159 patients in this study. Of them, 115 (72.3%) patients were male, 96 (60.4%) were ex/current smokers, their median age at diagnosis was 69 years, and ...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Respiratory infections Source Type: research
Conclusions: We report the largest retrospective nationwide cohort of patients hospitalized for CPA. In France, CPA is more commonly associated with COPD, emphysema, lung cancer or fibrosis than with TB. The alarming CPA morbidity and mortality rates observed should justify specific screening for CPA in some CPDs.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Respiratory infections Source Type: research
Conclusions: Examination of surgical material ensures verification of the diagnosis, determination of MDR/XDR MBT and lung cells, creates conditions for adequate chemotherapy. All of these proves the necessity of surgical treatment for lung tuberulomas.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Tuberculosis Source Type: research
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