Anaesthetic management of a patient diagnosed with amyotrophic lateral sclerosis taken to caesarean section: Case report

Conclusions Combined spinal-epidural anaesthesia was a good option as anaesthetic technique for caesarean section in this patient with amyotrophic lateral sclerosis.
Source: Colombian Journal of Anesthesiology - Category: Anesthesiology Source Type: research

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Authors: Marsli S, Mouni F, Araqi A, Elmoutawakil B, Elotmani H, Rafai MA PMID: 31548044 [PubMed - as supplied by publisher]
Source: Revue Neurologique - Category: Neurology Tags: Rev Neurol (Paris) Source Type: research
Conclusion The key problem with the ND field is the lack of understanding in the events preceding the development of protein-based markers – such as Tau – currently used to diagnose NDs. By this stage, the diseases become more difficult to treat. SncRNAs play an important regulatory role in the maintenance of the homeostatic brain. Therefore, changes in their concentration levels can be indicative of mechanistic changes that could precede protein-based markers. One single sncRNA biomarker is unlikely to differentiate between diseases. However, a combination of sncRNA biomarkers could be illustrative of the me...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
CONCLUSION: A literature search found 22 cases through PubMed and Ovid, with key words "amyotrophic lateral sclerosis" and "pregnancy." Both slow progression and rapid progression of ALS during pregnancy have been reported. Worsening of symptoms seems to be common, but little is still known about the influence of pregnancy on ALS onset and progression. PMID: 30528837 [PubMed - as supplied by publisher]
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research
A 25-year-old woman (G2P1) was diagnosed at 27 weeks-of-gestation with clinically definite amyotrophic lateral sclerosis (ALS), according to the revised El Escorial electrophysiological criteria.1 She was referred to the obstetrician for assessment of her pregnancy and to discuss the implications of ALS and delivery. Her previous pregnancy had been uneventful and she had a spontaneous vaginal delivery. At 28 weeks-of-gestation she was seen in consultation by an obstetrician and anesthesiologist.
Source: International Journal of Obstetric Anesthesia - Category: Anesthesiology Authors: Source Type: research
BY UWE REINHARDT In tribute to Uwe we are re-running this instant classic from THCB’s archives. Originally published on Jan 31, 2017. Everyone knows (or should know) that forcing a commercial health insurer to write for an individual a health insurance policy at a premium that falls short of the insurer’s best ex ante estimate of the cost of health care that individual will require is to force that insurer into what economists might call an unnatural act. Remarkably, countries that rely on competing private health insurers to operate their universal, national health insurance systems all do just that. They a...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Repeal Replace Trending Uwe Reinhardt Source Type: blogs
Conclusions: This large case-control study across 3 different countries has demonstrated an association between exogenous estrogens and progestogens and reduced odds of ALS in women. These results are at variance with previous findings, which may be partly explained by differential regulatory, social, and cultural attitudes toward pregnancy, birth control, and HRT across the countries included. Our results indicate that hormonal factors may be important etiologic factors in ALS; however, a full understanding requires further investigation.
Source: Neurology - Category: Neurology Authors: Tags: Amyotrophic lateral sclerosis, Case control studies, Risk factors in epidemiology ARTICLE Source Type: research
Steve and Kristie Matt met 13 years ago and have been married for 12 of those years. “We immediately knew we were the perfect match from the moment we met,” says Kristie. They also both worked in Philadelphia’s bar/restaurant industry for years—many of them side-by-side—with Steve cooking and Kristie tending bar. A little more than two years ago, Steve noticed hoarseness and low volume in his voice. Shortly thereafter, he began to experience weakness in his legs. Steve and Kristie Matt Diagnosed with bulbar-onset amyotrophic lateral sclerosis (ALS) in January 2016, Steve immediately jumpe...
Source: American Speech-Language-Hearing Association (ASHA) Press Releases - Category: Speech-Language Pathology Authors: Tags: Speech-Language Pathology ALS Dysphagia Swallowing Disorders Source Type: blogs
BY UWE REINHARDT Everyone knows (or should know) that forcing a commercial health insurer to write for an individual a health insurance policy at a premium that falls short of the insurer’s best ex ante estimate of the cost of health care that individual will require is to force that insurer into what economists might call an unnatural act. Remarkably, countries that rely on competing private health insurers to operate their universal, national health insurance systems all do just that. They allow each insurer to set the premium for a government-mandated , comprehensive benefit package, but require that each insurer...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Uncategorized Uwe Reinhardt Source Type: blogs
Cases of amyotrophic lateral sclerosis with pregnancy are quite rare. The aim of this case report is to present the successful use of total intravenous anesthesia without muscle relaxant for cesarean section in a parturient with amyotrophic lateral sclerosis at 35 weeks' gestation. The parturient presented with impaired neuromuscular function. Titrated general anesthesia with short-acting anesthetics was applied. During the procedure, no muscle relaxant was used. This strategy helped avoid prolonged ventilation and prevent maternal respiratory complications.
Source: Journal of Clinical Anesthesia - Category: Anesthesiology Authors: Tags: Case report Source Type: research
Abstract: The Guillain–Barré syndrome (GBS) is one of the few neuropathies well known to the general public, in part because of its association with swine flu vaccinations in 1976. GBS has again reached the general public with its possible association with Zika virus. The virus, borne by infected Aedes aegypti mosquitos, is being linked to birth defects when pregnant women are bitten and infected. There are early reports also linking GBS to Zika infection, which could expose a wider range of infected people to the neuropathy. This summer infected Aedes mosquitos will likely reach southern portions of the Unite...
Source: Journal of Clinical Neuromuscular Disease - Category: Neurology Tags: Literature Review Source Type: research
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