Mitochondria-Targeted Antioxidant Mito-Tempo Protects Against Aldosterone-Induced Renal Injury < b > < i > In Vivo < /i > < /b >

Conclusion: Mitochondria-targeted antioxidants may attenuate Aldo-infused renal injury by inhibiting MtD, the Nlrp3 inflammasome, and ERSin vivo. Therefore, targeting mtROS might be an effective strategy for preventing CKD.Cell Physiol Biochem 2017;44:741 –750
Source: Cellular Physiology and Biochemistry - Category: Cytology Source Type: research