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Child ’s science experiment solves chronic disease mystery

“Chew this.” I was instructed. “But don’t swallow. Just tell me when IT happens.” IT? What was IT? I’d have to find out. My researcher’s son — who enlisted me in his science experiment — wasn’t telling. So I obliged and started chewing. It tasted just as I expected at first. Bland. Almost cardboard-like. And then the strangest thing occurred. After about a minute, a hint of sweetness tickled my tongue. I kept chewing. A few seconds later, it intensified… like I was sucking on candy. And a few seconds after that it felt like I had an entire spoonful of sugar in my mouth. What happened? Like a shredder rips paper into little strips… my teeth and enzymes in my saliva broke down the complex molecules in the food. In a nutshell, simply chewing the food longer revealed what was REALLY inside the food. Now, the food I was asked to chew was what many people would consider harmless. Some would even call it healthy. A cracker. But as you’ve just seen, essentially it was no different than eating sugar. That’s right… the complex carbohydrates found in starchy foods like rice, pasta, and bread quickly turn into simple carbohydrates that have the same effect on your body as sugar. Which means they have the same harmful health effects on your body that sugar does. But so what? How much sugar can be in a cracker? A lot more than you would think. Just three measly crackers break down into the equivale...
Source: Al Sears, MD Natural Remedies - Category: Complementary Medicine Authors: Tags: Nutrition Weight Loss carbohydrates carbs disease sugar Syndrome Zero Source Type: news

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Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
This article discusses the challenges and outcomes of cataract surgery in complex cases targeting eyes with ocular surface diseases like Stevens–Johnson syndrome, ocular cicatricial pemphigoid, Mooren's ulcer, vernal keratoconjunctivitis and limbal stem cell deficiency. Recent findings Ocular surface diseases are commonly associated with corneal scarring and vascularization, conjunctival inflammation, symblepharon and forniceal shortening. Any surgical intervention in a hostile ocular surface environment may worsen the disease, which may result in visual deterioration. In recent past, with the use of immunosuppres...
Source: Current Opinion in Ophthalmology - Category: Opthalmology Tags: CATARACT SURGERY AND LENS IMPLANTATION: Edited by Natalie A. Afshari Source Type: research
In the research here, injections of blood plasma from young rats are shown to improve autophagy and liver function in old rats. This is interesting given the so far mixed evidence for young to old plasma transfer to be beneficial. There is, however, a history of research to show that increased levels of the cellular maintenance processes of autophagy can improve liver function in old rodents. Autophagy normally declines with age, and this appears to contribute to a variety of issues, such as loss of stem cell activity. You might recall that increasing the number of receptors on lysosomes in old rats can improve liver funct...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
Stem cells are up-and-coming therapies, and a major engineering problem has been scaling up the cell manufacturing to create enough cells for different therapeutic applications. Cytotwister, from the Industrial Technology Research Institute (ITRI) in Taiwan, makes a step towards solving that with a unique 3D stem cell bioreactor system that addresses common issues in stem cell harvesting and recovery. Their innovative device was a finalist for the R&D 100 Awards. We spoke with Dr. Hsin-Hsin Shen, Director of ITRI’s Regenerative Medicine Technologies Division about the Cytotwister, how it works, and how it will help m...
Source: Medgadget - Category: Medical Devices Authors: Tags: Exclusive Genetics Medicine Oncology Source Type: blogs
This article is protected by copyright. All rights reserved.
Source: Biotechnology Progress - Category: Biotechnology Authors: Tags: Biocatalysts and Bioreactor Design Source Type: research
In cycling human endometrium, menstruation is followed by rapid estrogen-dependent growth. Upon ovulation, progesterone and rising cellular cAMP levels activate the transcription factor Forkhead box O1 (FOXO1) in endometrial stromal cells (EnSCs), leading to cell cycle exit and differentiation into decidual cells that control embryo implantation. Here we show that FOXO1 also causes acute senescence of a subpopulation of decidualizing EnSCs in an IL-8 dependent manner. Selective depletion or enrichment of this subpopulation revealed that decidual senescence drives the transient inflammatory response associated with endometr...
Source: eLife - Category: Biomedical Science Tags: Human Biology and Medicine Source Type: research
This article is protected by copyright. All rights reserved
Source: Journal of Cellular Physiology - Category: Cytology Authors: Tags: MINI ‐REVIEW Source Type: research
This article is protected by copyright. All rights reserved
Source: Journal of Cellular Physiology - Category: Cytology Authors: Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
This study investigates if stem cells show protective effects on cardiomyocyte damage induced by porphyromonas gingivalis‐LPS (Pg‐LPS) through regulating miRNAs. H9c2 cardiomyoblasts and neonatal rat cardiomyocytes (NRCMs) were damaged using Pg‐LPS in this study. Pg‐LPS damaged H9c2 or NRCMs were then rescued using adipose‐derived stem cells (ADSC). The experimental results reveal that Pg‐LPS treatment is capable of inducing TLR4/NFκB axis activation, cell death signaling and IGF1R/PI3K/Akt axis suppression. miR181b was downregulated in Pg‐LPS damaged H9c2/NRCMs. All markers were improved in H9c2/NRCMs ...
Source: Journal of Cellular Physiology - Category: Cytology Authors: Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
AbstractThe traditional researcher-driven environment of medical knowledge production is losing its dominance with the expansion of, for instance, community-based participatory or participant-led medical research. Over the past few decades, sociologists of science have debated a shift in the production of knowledge from traditional discipline-based (Mode 1) to more socially embedded and transdisciplinary frameworks (Mode 2). Recently, scholars have tried to show the relevance of Mode 2 knowledge production to medical research. However, the existing literature lacks detailed clarifications on how a model of Mode 2 knowledge...
Source: Journal of Bioethical Inquiry - Category: Medical Ethics Source Type: research
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