Child ’s science experiment solves chronic disease mystery

“Chew this.” I was instructed. “But don’t swallow. Just tell me when IT happens.” IT? What was IT? I’d have to find out. My researcher’s son — who enlisted me in his science experiment — wasn’t telling. So I obliged and started chewing. It tasted just as I expected at first. Bland. Almost cardboard-like. And then the strangest thing occurred. After about a minute, a hint of sweetness tickled my tongue. I kept chewing. A few seconds later, it intensified… like I was sucking on candy. And a few seconds after that it felt like I had an entire spoonful of sugar in my mouth. What happened? Like a shredder rips paper into little strips… my teeth and enzymes in my saliva broke down the complex molecules in the food. In a nutshell, simply chewing the food longer revealed what was REALLY inside the food. Now, the food I was asked to chew was what many people would consider harmless. Some would even call it healthy. A cracker. But as you’ve just seen, essentially it was no different than eating sugar. That’s right… the complex carbohydrates found in starchy foods like rice, pasta, and bread quickly turn into simple carbohydrates that have the same effect on your body as sugar. Which means they have the same harmful health effects on your body that sugar does. But so what? How much sugar can be in a cracker? A lot more than you would think. Just three measly crackers break down into the equivale...
Source: Al Sears, MD Natural Remedies - Category: Complementary Medicine Authors: Tags: Nutrition Weight Loss carbohydrates carbs disease sugar Syndrome Zero Source Type: news

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In conclusion, these results suggest that allogenic ADSCs in combination with PRF can accelerate regeneration in full-thickness cartilage defects in the rabbit ear model without causing a significant immune response. The results suggest that allogenic ADSCs with PRF could successfully be used for cartilage regeneration. PMID: 30018729 [PubMed]
Source: American Journal of Translational Research - Category: Research Tags: Am J Transl Res Source Type: research
CONCLUSION: The present study suggested that the repair effect of nasal mucosa-derived MSCs in orbital fracture is achieved by facilitating the expressions of osteogenic markers Runx2, OCN, OPN and BSP. However, the pathways of actions are unknown and further studies are required to elucidate the concrete mechanism. PMID: 30018713 [PubMed]
Source: American Journal of Translational Research - Category: Research Tags: Am J Transl Res Source Type: research
This study examines the therapeutic effects of transplantation of Nurr1 gene-modified bone marrow mesenchymal stem cells (MSCs) on 6-hydroxydopamine (6-OHDA)-induced PD rat models. MSCs were transduced with lentivirus expressing Nurr1 gene and then intrastriatally transplanted into PD rats. Our results showed that Nurr1 gene-modified MSCs overexpress and secrete Nurr1 protein in vitro and also survive and migrate in the brain. Four weeks after transplantation Nurr1 gene-modified MSCs dramatically ameliorated the abnormal behavior of PD rats and increased the numbers of tyrosine hydroxylase (TH)-positive cells in the substa...
Source: American Journal of Translational Research - Category: Research Tags: Am J Transl Res Source Type: research
Acute kidney injury (AKI) is a common complication in cancer patients and occurs in up to 30% of patients during their disease course. Multiple myeloma, leukemia/lymphoma, renal cell carcinoma, and hematopoietic stem cell transplantation are commonly associated with the development of AKI.07/19/2018
Source: Kidney Cancer Association - Category: Urology & Nephrology Source Type: news
Conclusion: FGF-2 gene overexpression lentivirus transfection BMSCs combined with XACB to construct tissue engineered bone can effectively promote vascular regeneration, and improve the repair effect of avascular necrosis of the femoral head.Cell Physiol Biochem 2018;48:773 –784
Source: Cellular Physiology and Biochemistry - Category: Cytology Source Type: research
Condition:   Allogeneic Hematopoietic Stem Cell Transplantation Intervention:   Behavioral: Humor therapy Sponsors:   Universitätsklinikum Hamburg-Eppendorf;   Deutsche José Carreras Leukämie-Stiftung;   Staburo GmbH Recruiting
Source: - Category: Research Source Type: clinical trials
Conditions:   Infertility, Female;   Endometrium Intervention:   Procedure: UC-MSCs therapy Sponsor:   The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School Recruiting
Source: - Category: Research Source Type: clinical trials
Publication date: Available online 18 July 2018Source: Mechanisms of Ageing and DevelopmentAuthor(s): Shanrong Bi, Hanyu Wang, Weihong KuangAbstractStem cells being pluripotent in nature can differentiate into a wide array of specific cells and asymmetrically divide to produce new ones but may undergo aging by themselves. Aging has both quantitative and qualitative effects on stem cells, and could eventually restrain them from replenishing into progenitor cells. Reactive oxygen species (ROS) accumulated in the aging cells could not only block the cell cycle but also affect autophagy by damaging the mitochondria. Autophagy ...
Source: Mechanisms of Ageing and Development - Category: Geriatrics Source Type: research
Authors: Michelerio A, Kirsh A, Croci GA, Colombo AA, Bernasconi P, Paulli M, Brazzelli V, Vassallo C PMID: 30014683 [PubMed - as supplied by publisher]
Source: Giornale Italiano di Dermatologia e Venereologia - Category: Dermatology Tags: G Ital Dermatol Venereol Source Type: research
Sharad Kholia, Maria Beatriz Herrera Sanchez, Massimo Cedrino, Elli Papadimitriou, Marta Tapparo, Maria Chiara Deregibus, Maria Felice Brizzi, Ciro Tetta, Giovanni Camussi
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
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