The divergent impact of catechol-O-methyltransferase (COMT) Val158Met genetic polymorphisms on executive function in adolescents with discrete patterns of childhood adversity

Catechol-O-methyltransferase (COMT) Val158Met functional polymorphisms play a crucial role in the development of executive function (EF), but their effect may be moderated by environmental factors such as childhood adversity. The present study aimed at testing the divergent impact of the COMT Val158Met genotype on EF in non-clinical adolescents with discrete patterns of childhood adversity.

Source: Comprehensive Psychiatry - November 22, 2017 Category: Psychiatry Authors: Huihui Zhang, Jie Li, Bei Yang, Tao Ji, Zhouting Long, Qiquan Xing, Di Shao, Huayu Bai, Jiwei Sun, Fenglin Cao Source Type: research