The Protean Neuropsychiatric and Vestibuloauditory Manifestations of Neurosarcoidosis

Conclusions: Neurosarcoidosis is an elusive diagnosis and can cause hearing loss and psychiatric symptoms. Cochlear implantation for patients with severe hearing loss should be considered once the diagnosis is confirmed, as it is possible to achieve a successful level of hearing. Psychiatric symptoms can manifest with the onset of neurosarcoidosis, result from CN deficits, or develop as a side effect from long-term, high-dose corticosteroids, and should be monitored carefully in patients with neurosarcoidosis.Audiol Neurotol 2017;22:205-217
Source: Audiology and Neurotology - Category: Audiology Source Type: research

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This study compared the best corrected visual acuity (BCVA), surgically induced astigmatism (SIA), endothelial cell loss, and patient satisfaction between corneal section phacoemulsification (CSP) and Blumenthal manual small incision cataract surgery (MSICS).MethodsIn this pragmatic study, following pre-operative assessment, patients made a choice to undergo either CSP or MSICS after the options were explained by the ophthalmologist. Pre- and post-operative (Day 1, 1-week, 6-weeks) refraction, keratometry and specular microscopy were performed. Subjective improvement in visual function was assessed before surgery and at 6-...
Source: Clinical Epidemiology and Global Health - Category: Epidemiology Source Type: research
After being told disease would destroy her vision, Paola Peretti wrote a children ’s novel – and found a template for lifePaola Peretti is losing her eyesight and she wouldn ’t have it any other way. When she was 14, she became very short-sighted, virtually overnight. Three years later came the diagnosis ofStargardt macular dystrophy, a degenerative disease that destroys central vision, damages colour perception and results in blindness. Two years ago, finding herself in a place of both “desperation and hope,” the 32-year-old Italian language teacher and debut novelist decided to step out from...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Blindness and visual impairment Books Disability Health Culture Society Psychology Science Life and style & wellbeing Source Type: news
ConclusionsThough the available literature is mostly short-term, there is evidence that lithium monotherapy is reasonably safe and effective in children and adolescents, specifically for acute mania and for prevention of mood episodes.
Source: European Psychiatry - Category: Psychiatry Source Type: research
The trouble began when I needed to open the electronic health record (EHR) system for the tenth time that day. EHRs have significantly changed the way we practice medicine. They have completely eliminated the need for storage and transport of paper charts, reduced prescription errors secondary to illegible handwritings of physicians and provided an excellent platform to maximize billing for services rendered. However, in terms of creating a smooth workflow for physicians and in facilitating meaningful face to face encounters with our patients, all EHR systems have completely failed. Sara, the nurse for Ms. Tucker, called m...
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Tech Cardiology Health IT Hospital-Based Medicine Source Type: blogs
Authors: Garnacho-Montero J, Barrero-García I, Gómez-Prieto MG, Martín-Loeches I Abstract INTRODUCTION: Despite advances in modern medicine, severe community-acquired pneumonia (CAP) continues to be a potentially deadly disease. Mortality rate reaches up to the 50% in patients requiring admission to the Intensive Care Unit (ICU) when developing septic shock. Areas covered: We aim to describe the optimal management of severe CAP including antibiotic therapy, future antimicrobial options, and non-antibiotic (so-called adjunctive) therapies. A literature search was performed to identify all clinic...
Source: Expert Review of Anti-Infective Therapy - Category: Infectious Diseases Tags: Expert Rev Anti Infect Ther Source Type: research
Authors: Al-Nemrawi NK, Marques J, Tavares CJ, Oweis RJ, Al-Fandi MG Abstract The aim of this work is to prepare ultraviolet (UV) triggered controlled release of compounds from microcapsule systems (MCs). Polyurethane (PU) and poly(methyl methacrylate) (PMMA) microcapsules were studied with/without chemical functionalization using photocatalytic TiO2 nanoparticles (NPs) on their surface. Once TiO2 nanoparticles are illuminated with UV light (λ = 370nm) they initiate the rupture of the polymeric bonds of the microcapsule and subsequently initiate the encapsulated compound release, methotrexate (MTX) or rhodam...
Source: Drug Development and Industrial Pharmacy - Category: Drugs & Pharmacology Tags: Drug Dev Ind Pharm Source Type: research
In conclusion, curcumin can be used as a potential and safe drug in the management of patients with remission and mild-to-moderate UC. PMID: 30111198 [PubMed - as supplied by publisher]
Source: Immunopharmacology and Immunotoxicology - Category: Allergy & Immunology Tags: Immunopharmacol Immunotoxicol Source Type: research
CLINICAL MANAGEMENT OF RHEUMATOLOGIC CONDITIONSCO-OCCURRING WITH INFLAMMATORY BOWEL DISEASES. Expert Rev Clin Immunol. 2018 Aug 17;: Authors: Felice C, Pugliese D, Papparella LG, Pizzolante F, Onori E, Gasbarrini A, Rapaccini GL, Guidi L, Armuzzi A Abstract INTRODUCTION: Spondyloarthritis (SpA) is the most common extra-intestinal manifestation in patients with inflammatory bowel diseases (IBD). Articular disorders may also appear as "paradoxical" effects during biologic therapy with anti-tumor necrosis factor (TNF). Areas covered: In this narrative review, we report the current knowledge abou...
Source: Expert Review of Clinical Immunology - Category: Allergy & Immunology Tags: Expert Rev Clin Immunol Source Type: research
Publication date: Available online 18 August 2018Source: Meta GeneAuthor(s): Samar Amin, Tareq A. Wani, Zahoor Ahmad Kaloo, Seema Singh, Riffat John, Umer Majeed, Gowhar Ahmad ShapooAbstractInula royleana (Asteraceae) is a perennial medicinal herb native to Western Himalaya. In Kashmir Himalaya it is commonly known as ‘GugiPhool’. The plant has been traditionally used for various putative health benefits like headache, intestinal problems and blood pressure. The plant is rich source of alkaloids and other metabolites. The important medicinal properties which include antimicrobial, anti-inflammatory, antiprolife...
Source: Meta Gene - Category: Genetics & Stem Cells Source Type: research
Authors: Xu Y, Yu S, Zhang L, Zheng J, Chen Y, Che Y Abstract Application value of iterative reconstruction with computed tomographic angiography (CTA) in the patients with intractable headache was investigated. One hundred and eighty patients with headache, who were admitted and treated in Cangzhou Central Hospital, were selected to undergo CTA scan. The patients were divided into group A, B and C according to different scanning conditions and data reconstruction techniques. In group A, the scanning parameters were 120 kV and 300 mA, and filtered back projection (FBP) algorithm was used for data reconstruction. In...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
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