Effectiveness, Implementation and Real-World Experience with Extended-Release Naltrexone (XR-NTX): A Special Issue of JSAT

Extended-release naltrexone (XR-NTX) has several properties that make it an important addition to the pharmacopoeia for addictive disorders. It has no abuse potential, is administered monthly and, creating no physiological dependence, has no withdrawal syndrome on discontinuation. As a result, XR-NTX has generated great interest for the treatment of alcohol and opioid use disorders in settings where agonist therapies have been less accepted, such as “abstinence-oriented” treatment programs, drug court and community reentry after incarceration.

Source: Journal of Substance Abuse Treatment - November 21, 2017 Category: Addiction Authors: Peter D. Friedmann, Kelly E. Dunn, Edward V. Nunes, Charles P. O ’Brien Source Type: research