In vitro and in vivo activity of fosfomycin alone and in combination with rifampin and tigecycline against Gram-positive cocci isolated from surgical wound infections.

In conclusion, the efficacy of fosfomycin combinations, also confirmed in our in vivo model, may suggest new directions in the treatment of infected skin and a possible alternative way to control bacterial skin infection. PMID: 29154746 [PubMed - as supplied by publisher]
Source: Journal of Medical Microbiology - Category: Microbiology Authors: Tags: J Med Microbiol Source Type: research

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Researchers have developed a self-cleaning plastic wrap that repels bacteria -- and could be used to prevent the transfer of antibiotic resistant superbugs, and other forms of dangerous bacteria.
Source: - Health - Category: Consumer Health News Source Type: news
Authors: Bourée P PMID: 31825188 [PubMed - in process]
Source: Bulletin de la Societe de Pathologie Exotique - Category: Tropical Medicine Tags: Bull Soc Pathol Exot Source Type: research
Publication date: Available online 12 December 2019Source: Food Science and Human WellnessAuthor(s): Yingying Zhao, Dandan Xia, Panpan Ma, Xiaofeng Gao, Wenyi Kang, Jinfeng WeiAbstractHuman health is threatened by foodborne illness and Staphylococcus aureus is a common foodborne pathogenic bacteria. It can cause food poisoning when we are infected, therefore, it is necessary to detect pathogenic bacteria. The virulence genes and detection methods of S. aureus are summarized from literatures. Traditional detection methods are simple but need bacteria enrichment and to prolong detection time. Immunological technology has hig...
Source: Food Science and Human Wellness - Category: Food Science Source Type: research
Publication date: Available online 12 December 2019Source: Biocatalysis and Agricultural BiotechnologyAuthor(s): Abdelhakim Bouyahya, Fatima Lagrouh, Naser El Omari, Ilhame Bourais, Meryem El Jemli, Ilias Marmouzi, Najoua Salhi, Faouzi My El Abbes, Omar Belmehdi, Nadia Dakka, Youssef BakriAbstractThe aim of this study was the investigation of the in vitro antioxidant, antidiabetic, dermatoprotective, antidermatophyte, and antibacterial properties of Mentha viridis essential oil (MVEO). Chemical composition of MVEO was determined using GC-MS analysis. Antioxidant activity was estimated by three complementary methods: DPPH, ...
Source: Biocatalysis and Agricultural Biotechnology - Category: Biotechnology Source Type: research
Publication date: Available online 12 December 2019Source: Journal of Saudi Chemical SocietyAuthor(s): Mohit Sanduja, Jyoti Gupta, Harbinder Singh, Piyusha P. Pagare, Abhineet RanaAbstractIn the current report, we have rationally designed a series of uracil-coumarin based bifunctional molecular hybrids roped by 1,2,3-triazole moiety. The designed compounds were synthesized and tested against a panel of six human cancer cell lines namely Colo-205, MCF-7, A-549, PA-1, PC-3 and Hela cells by Sulforhodamine B assay. The results indicated that the hybrid molecules can specifically inhibit the MCF-7 cancer cell proliferation amo...
Source: Journal of Saudi Chemical Society - Category: Chemistry Source Type: research
In this study, Mg-based composite fabricated by semi powder metallurgy was reinforced by graphene nano-platelets (GNPs). Scanning electron microscopy coupled with energy dispersive X-ray analysis (SEM/EDAX), transmission electron microscopy (TEM), Raman spectroscopy techniques and X-ray diffraction (XRD) analysis were used for microstructural, elemental and phase analyses. Microstructural evolution showed the uniform distribution of GNPs for the Mg-based composite with low GNPs concentration, but partial agglomeration could be seen in the composite containing a large amount of GNPs. Experimental results showed that hardnes...
Source: Journal of Alloys and Compounds - Category: Chemistry Source Type: research
Methicillin-resistant/susceptible Staphylococcus aureus (MRSA/MSSA) and Enterococcus faecalis strains are often found in community- and hospital-acquired infections. The single use of conventional antibiotics hardly completely kills the bacterial cells of interest, especially in the form of biofilms. Thus, drug repurposing and antimicrobial combination are promising ways to solve this problem. Antimicrobial susceptibility assays against cocci in a suspension and in a biofilm mode of growth were performed with broth microdilution methods. Checkerboard assays and the cutaneous mouse infection model were used to examine the a...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
CONCLUSIONS: We observed significantly higher isolations of E-ESPAKE MDR strains in patients with hematological malignancies. PMID: 29738654 [PubMed - in process]
Source: Salud Publica de Mexico - Category: Epidemiology Authors: Tags: Salud Publica Mex Source Type: research
Abstract To evaluate the in vitro antimicrobial activities of tedizolid, linezolid and other comparators against clinically significant Gram-positive cocci isolates from hospital-acquired pneumonia (HAP), skin and soft tissue infection (SSTI) and bloodstream infection (BSI), 2140 non-duplicate isolates (23.7% isolated from HAP, 46.8% from SSTI and 29.5% from BSI) were consecutively collected in 26 hospitals in 17 cities across China during 2014. These pathogens included 632 methicillin-resistant Staphylococcus aureus (MRSA), 867 methicillin-sensitive S. aureus (MSSA), 299 coagulase-negative Staphylococcus (CoNS), ...
Source: Journal of Medical Microbiology - Category: Microbiology Authors: Tags: J Med Microbiol Source Type: research
Conclusions: We believe these infections are a result of combining pertuzumab with trastuzumab as 2 pts received no concurrent chemotherapy. An awareness of this complication is critical as some infections may be life-threatening. We have initiated patient education to ensure awareness of this potential complication.Citation Format: Mortimer JE, Yuan Y, Jung J, Kruper L, Stewart D, Chung S, Yu WK, Mendelsohn M, D'Apuzzo M, Tegtmeier B, Dadwal S. Skin, and nail, infections associated with the addition of pertuzumab to trastuzumab-based chemotherapy. [abstract]. In: Proceedings of the Thirty-Eighth Annual CTRC-AACR San Anton...
Source: Cancer Research - Category: Cancer & Oncology Authors: Tags: Poster Session Abstracts Source Type: research
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