Children with Alagille Syndrome have malformed bile ducts

(Karolinska Institutet) Serious liver and heart problems can affect children with Alagille Syndrome early in life. While there is as yet no cure, researchers at Karolinska Institutet in Sweden have discovered that the liver disease part of the syndrome is caused by specific malformations of the bile ducts. The results, which are published in the journal Gastroenterology, were discovered with the aid of a new mouse model that can now be used to develop and test new therapies.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news