Imaging characteristics of subcutaneous amyloid deposits in diabetic patients: the “insulin ball”

ConclusionsSubcutaneous amyloid deposits which cause insulin resistance are typically ill-defined and heterogeneous hypovascular subcutaneous nodules with irregular margins on imaging that correspond to insulin injection sites. It is also characteristic that T2WI shows low intensity compared with fat on MRI, reflective of the amyloid content.
Source: Skeletal Radiology - Category: Radiology Source Type: research