Lacosamide pharmacokinetics in a critically ill patient receiving continuous venovenous hemofiltration

ConclusionLacosamide was cleared by CVVH as demonstrated by the sieving coefficient, but plasma concentrations remained within goal range throughout the dosing interval. These results may suggest that lacosamide 200 mg twice daily is a useful dosing strategy for critically ill patients who require CVVH.This article is protected by copyright. All rights reserved.

Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - November 1, 2017 Category: Drugs & Pharmacology Authors: Miguel J. Franquiz, Shamir N. Kalaria, Michael J. Armahizer, Mathangi Gopalakrishnan, Paul J. McCarthy, Neeraj Badjatia Tags: Case Report Source Type: research