Self-Destructive Behavior among Full-Donor Blood and Marrow Grafts and the Association with Long-Term Graft Function

Research will always bring new insights and new treatment options for well-established clinical conditions. A study in this issue of Biology of Blood and Marrow Transplantation presents interesting similarities in the biology and treatment of patients with late graft failure and acquired aplastic anemia: Maruyama et  al report a retrospective single center cohort of 14 patients with late graft failure, defined as at least two cytopenic cell lines, and full donor chimerism1. In this cohort, the authors investigated the presence of previously established markers for immune-mediated bone marrow failure2, 3.
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Source Type: research