NAFLD Linked to Increased Cancer Incidence Rate

NAFLD strongly tied to development of hepatocellular carcinoma, CRC in males, breast cancer in females
Source: The Doctors Lounge - Oncology - Category: Cancer & Oncology Tags: Family Medicine, Gastroenterology, Gynecology, Internal Medicine, Nursing, Oncology, Pathology, Radiology, Journal, Source Type: news

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ConclusionA DTF-specific HRQL tool and consensus regarding the preferred measurement tool among DTF patients is lacking. Our study indicates that HRQL of DTF patients was negatively affected in several domains. A DTF-specific HRQL measure could improve our understanding of short- and long-term effects and, ideally, can be used in both clinic and for research purposes.
Source: Quality of Life Research - Category: Health Management Source Type: research
Authors: Vajaitu C, Draghici CC, Solomon I, Lisievici CV, Popa AV, Lupu M, Caruntu C, Constantin MM, Voiculescu VM Abstract An important function of the immune system is its ability to differentiate between healthy cells in the organism and "foreign" cells, allowing the latest to be attacked and the first ones to be conserved. The most important molecules in this process are considered to be checkpoint inhibitors. This review is focused on the association between cancer and inflammation, underlying the mechanisms of action of monoclonal antibodies that are targeting checkpoint inhibitors: ipilimumab again...
Source: Journal of Immunology Research - Category: Allergy & Immunology Tags: J Immunol Res Source Type: research
CONCLUSIONS: Acknowledging the limitations of a retrospective analysis, our study confirms previous real-world evidence suggesting that continuing advances in the treatment of mRCC has led to improved outcomes in everyday practice worldwide. Pharmacoeconomic analyses are important for cost effective utilization of emerging novel therapies. PMID: 30417707 [PubMed - as supplied by publisher]
Source: Expert Review of Pharmacoeconomics and Outcomes Research - Category: Health Management Tags: Expert Rev Pharmacoecon Outcomes Res Source Type: research
Authors: Zhou J, Zheng S, Liu T, Liu Q, Chen Y, Ma R, Tan D, Lu X Abstract Although M2 tumour-associated macrophages (M2 TAMs) have been shown to be associated with the progression and metastasis of breast cancer, their role in oesophageal squamous cell carcinoma (ESCC) remains less well understood. Therefore, to understand the clinicopathological significance of infiltrated M2 TAMs in ESCC, statistical analysis was performed after immunohistochemical evaluation of CD163 expression, a well-accepted surface marker of M2 TAMs in ESCC. To gain insight into the effect of M2 TAMs, ESCC cell lines Eca109 and KYSE150 cell...
Source: Histology and Histopathology - Category: Cytology Tags: Histol Histopathol Source Type: research
Kits to self-test for human papillomavirus (HPV) mailed to underserved women helped to identify virtually all of those with high-risk HPV oncogenic types, in a proof-of-principle study.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health News Source Type: news
We appreciate Bo Zheng et al. for their interest in our study and for providing a valuable comment. Our study investigated the little understood relationship between non-alcoholic fatty liver disease (NAFLD) and extrahepatic cancers [1], and found that NAFLD was highly associated with the development of hepatocellular carcinoma (HCC), colorectal cancer in males, and breast cancer in females. This association suggests that NAFLD can serve as a risk factor of extrahepatic malignancies.
Source: Journal of Hepatology - Category: Gastroenterology Authors: Tags: Letter to the Editor Source Type: research
We read with great interests the article by Gi-Ae et al[1]. Non-alcoholic fatty liver disease(NAFLD) is strongly associated with metabolic disorders such as insulin resistance, diabetes and cardiovascular diseases which implies that NAFLD might have an important part in extrahepatic complications. Gi-Ae et al not only confirmed that NAFLD is closely related to the development of hepatocellular carcinoma but also demonstrated that NAFLD is a risk factor for extrahepatic malignancies such as male colorectal carcinoma and female breast cancer.
Source: Journal of Hepatology - Category: Gastroenterology Authors: Source Type: research
We thank Bo Zheng et al. for their interest in our study and for providing a valuable comment.1 Our study investigated the little understood relationship between non-alcoholic fatty liver disease (NAFLD) and extrahepatic cancers,2 and found that NAFLD was highly associated with the development of hepatocellular carcinoma (HCC), colorectal cancer in males, and breast cancer in females. This association suggests that NAFLD can serve as a risk factor of extrahepatic malignancies.
Source: Journal of Hepatology - Category: Gastroenterology Authors: Tags: Letter to the Editor Source Type: research
We read with great interest the article by Kim et al.1 Non-alcoholic fatty liver disease (NAFLD) is strongly associated with metabolic disorders such as insulin resistance, diabetes and cardiovascular disease, suggesting that NAFLD is an important factor in extrahepatic complications. Kim et al. not only confirmed that NAFLD is closely related to the development of hepatocellular carcinoma, but also demonstrated that NAFLD is a risk factor for extrahepatic malignancies such as male colorectal carcinoma and female breast cancer.
Source: Journal of Hepatology - Category: Gastroenterology Authors: Tags: Letter to the Editor Source Type: research
We thank Bo Zheng et al. for their interest in our study and for providing a valuable comment.1 Our study investigated the little understood relationship between non-alcoholic fatty liver disease (NAFLD) and extrahepatic cancers,2 and found that NAFLD was highly associated with the development of hepatocellular carcinoma (HCC), colorectal cancer in males, and breast cancer in females. This association suggests that NAFLD can serve as a risk factor of extrahepatic malignancies.
Source: Journal of Hepatology - Category: Gastroenterology Authors: Tags: Letter to the Editor Source Type: research
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