Effect of magnesium supplementation and depletion on the onset and course of acute experimental pancreatitis

Conclusions
Magnesium supplementation significantly reduces premature protease activation and the severity of pancreatitis, and antagonises pathological [Ca2+]i signals. Nutritional magnesium deficiency increases the susceptibility of the pancreas towards pathological stimuli. These data have prompted two clinical trials on the use of magnesium in patients at risk for pancreatitis.

Source: Gut - August 3, 2014 Category: Gastroenterology Authors: Schick, V., Scheiber, J. A., Mooren, F. C., Turi, S., Ceyhan, G. O., Schnekenburger, J., Sendler, M., Schwaiger, T., Omercevic, A., Brandt, C. v. d., Fluhr, G., Domschke, W., Kruger, B., Mayerle, J., Lerch, M. M. Tags: Pancreas and biliary tract, Pancreatitis Source Type: research