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Blueprint to reduce wasteful blood transfusions

(Johns Hopkins Medicine) By analyzing data from randomized clinical trials comparing blood transfusion approaches, Johns Hopkins experts, along with colleagues at Cleveland Clinic and NYU Langone Medical Center, endorse recommendations for blood transfusions that reduce blood use to improve patient safety and outcomes. Publishing this week in JAMA Internal Medicine, the report also provides a how-to guide for launching a patient blood management program.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news

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Source: Indian Journal of Hematology and Blood Transfusion - Category: Hematology Source Type: research
BACKGROUND: Reducing time from injury to care can optimize trauma patient outcomes. A previous study of prehospital transport of US military casualties during the Afghanistan conflict demonstrated the importance of time and treatment capability for combat ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Conclusions:Sp-Hb showed accurate precision in both absolute values and trend values compared with Lab-Hb measurement in trauma patients with low hemoglobin levels. Objective: Bleeding is a leading cause of death among trauma patients. Delayed assessment of blood hemoglobin level might result in either unnecessary blood transfusion in nonindicated patients or delayed blood transfusion in critically bleeding patients. In this study, we evaluate the precision of noninvasive hemoglobin monitoring in trauma patients with low hemoglobin levels. Methods: We included trauma patients with low hemoglobin levels (less than 8...
Source: Shock - Category: Emergency Medicine Tags: Clinical Science Aspects Source Type: research
AbstractBackgrounds/aimsAlthough post-polypectomy bleeding is the most frequent complication after colonoscopic polypectomy, only few studies have investigated the incidence of bleeding prospectively. The aim of this study was to investigate the incidence of delayed post-polypectomy bleeding and its associated risk factors prospectively.MethodsPatients who underwent colonoscopic polypectomy at Kangbuk Samsung Hospital from January 2013 to December 2014 were prospectively enrolled in this study. Trained nurses contacted patients via telephone 7 and 30  days after polypectomy and completed a standardized questionnaire r...
Source: Surgical Endoscopy - Category: Surgery Source Type: research
AbstractPurposeTo evaluate the impact of timing of blood transfusion in patients with upper tract urothelial carcinoma (UTUC) treated with radical nephroureterectomy (RNU).MethodsOutcomes of consecutive patients with UTUC treated with RNU were analyzed. Clinicopathologic factors were compared using Fisher ’s exact test or the Wilcoxon rank-sum test between patients who received any transfusion and no transfusion, and between patients receiving intraoperative transfusion only and patients receiving no transfusion. Cancer-specific and overall survival were estimated and multivariable analyses were pe rformed to assess ...
Source: World Journal of Urology - Category: Urology & Nephrology Source Type: research
The FDA and the Pentagon said today that they’re launching a joint program to speed the development of medical products for military personnel. The federal safety watchdog and the Defense Dept.’s Office of Health Affairs said the program’s framework is based on a House bill passed last year that expands the FDA’s authority to approve the emergency use of unapproved medical treatments and aims to expedite the approval process. Critics claim the program could erode medical safety, putting U.S. soldiers at risk. “Utilizing this law’s expanded authorities, the FDA will work closely...
Source: Mass Device - Category: Medical Devices Authors: Tags: Food & Drug Administration (FDA) Regulatory/Compliance defensedepartment Source Type: news
Question: A 62-year-old man was referred to our hospital with 2 years of recurrent symptomatic melena requiring multiple blood transfusions and iron therapy. His past medical history was not significant. His physical examination was unremarkable and laboratory tests were significant for mild anemia (hemoglobin, 11 g/L; mean corpuscular volume, 96.9 fL). Initial bidirectional endoscopy revealed small amount of hematin stain in the hepatic flexure and mild ileum erythema was found on capsule endoscopy (Figure A).
Source: Gastroenterology - Category: Gastroenterology Authors: Tags: Clinical Challenges and Images in GI Source Type: research
ConclusionsSingle-incision laparoscopic hepaticojejunostomy is safe and effective for selected patients with perforated CDCs in experienced hands.
Source: Surgical Endoscopy - Category: Surgery Source Type: research
ConclusionsFVL was more prevalent among SS patients compared to controls and it was associated with higher incidence of disease complications among SCD patients.
Source: BMC Hematology - Category: Hematology Source Type: research
AbstractAvoidance of red blood cell (RBC) transfusions in patients awaiting heart transplantation (HTx) has been suggested to minimize the risk of allosensitization. Although recent studies have suggested that an immature immune system in younger HTx recipients may reduce risks associated with RBC transfusion, the role of age in moderating the influence of transfusion on HTx outcomes remains unclear. We used available data from a national transplant registry to explore whether the association between pre-transplant transfusions and outcomes of pediatric HTx varies by patient age. De-identified data were obtained from the U...
Source: Pediatric Cardiology - Category: Cardiology Source Type: research
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