Blueprint to reduce wasteful blood transfusions
(Johns Hopkins Medicine) By analyzing data from randomized clinical trials comparing blood transfusion approaches, Johns Hopkins experts, along with colleagues at Cleveland Clinic and NYU Langone Medical Center, endorse recommendations for blood transfusions that reduce blood use to improve patient safety and outcomes. Publishing this week in JAMA Internal Medicine, the report also provides a how-to guide for launching a patient blood management program.
ConclusionA paradigm shift in the approach to management of biliary strictures complicating LDLT is proposed whereby a multidimensional definition of FSO can help in reliable patient selection for endotherapy and improve patient outcome as a whole.
ConclusionThis case suggests that even if great vessel injury is not detected on contrast CT at admission, it should always be considered especially in a hemothorax case with multiple rib fractures.
Publication date: Available online 14 February 2020Source: European Journal of Obstetrics &Gynecology and Reproductive BiologyAuthor(s): Dubravko Habek, Anis Cerovac, Ana Luetić, Ingrid Marton, Matija Prka, Tomislav Kulaš, Boris UjevićAbstractObjectiveA 15-year-experience of the personal modification of Misgav Ladach (ML) caesarean section in relation to the Dörffler method.Study designA retrospective clinical randomized observational study included 822 transperitoneal cesarean sections: 557 were performed via modified ML (without bladder catheterization, small transverse fascial incision with muscular st...
[Nation] Dr Fridah Govedi walked into the Kenya National Blood Transfusion Services (KNBTS) in early August last year, just a few days after the Centers for Disease Control and Prevention (CDC), Kenya stopped funding the department, and after the former director, Dr Josephine Githaiga, left in July.
ConclusionsIn JWs undergoing cardiac surgery who refuse alloBT, intraoperative use of 4PCC was not associated with a difference in Hgb change within 7 days postoperatively when adjusting for confounding variables. In the event of excessive blood loss, the utilization of 4PCC may provide a viable option in JW patients who undergo cardiac surgery where few options exist to mitigate blood loss.
Conclusions: Resuscitation from HS via transfusion of anaerobically stored RBCs recovered cardiac function, restored hemodynamic stability, and improved outcomes.
RARITAN, NJ, February 10, 2020 – The Janssen Pharmaceutical Companies of Johnson &Johnson announced today the submission of a supplemental Biologics License Application (sBLA) to the U.S. Food and Drug Administration (FDA) seeking approval of DARZALEX® (daratumumab) in combination with Kyprolis® (carfilzomib) and dexamethasone (DKd) for relapsed/refractory multiple myeloma. The sBLA is supported by results from the Phase 3 CANDOR study, which compared treatment with DKd to carfilzomib and dexamethasone (Kd) in patients with multiple myeloma who relapsed after one to three prior lines of therapy. “Wh...
ConclusionAnesthetic management is essential in scenarios such as the one reported to assure patient survival.ResumoIntroducãoA hemicorporectomia cursa com repercussões hemodinâmicas e ventilatórias que fazem o manejo anestésico ser definitivo para o desfecho do paciente.ObjetivoRelatar a condução anestésica em um portador de carcinoma espinocelular submetido à hemicorporectomia de urgência após episódio de choque hipovolêmico.Relato de casoApós sangramento pela lesão, paciente apresentou choque hipovolêmico classe 3...
CONCLUSION: This study reinforces the relevance of developing integrated and rational responses of health services and provides evidence for this. PMID: 32035495 [PubMed - in process]