Impact of an oral appliance on obstructive sleep apnea severity, quality of life, and biomarkers

ConclusionsUse of a MAD significantly improved polysomnographic parameters, quality of life, and some inflammatory markers (CRP, IL‐β, and TNF‐α) in a significant proportion of patients with moderate OSA and in some patients with severe OSA. Hence, a MAD may be a viable alternative therapy in patients with moderate‐to‐severe OSA who refuse continuous positive airway pressure. Level of Evidence3b Laryngoscope, 2017

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1002%2Flary.26913

Source: The Laryngoscope - November 20, 2017 Category: ENT & OMF Authors: Enrique Fern ández‐Julián, Tomás Pérez‐Carbonell, Rocío Marco, Verónica Pellicer, Enrique Rodriguez‐Borja, Jaime Marco Tags: Sleep Medicine Source Type: research