[Pathogenesis, genetics and diagnosis of endometriosis].

[Pathogenesis, genetics and diagnosis of endometriosis].
Presse Med. 2017 Nov 14;:
Authors: Daraï E, Ploteau S, Ballester M, Bendifallah S
Abstract
Endometriosis is a multifactorial pathology. Trans-tubal reflux theory remains valid. Genetic and epigenetic factors associated with immunological perturbations are involved. The role of endocrine disruptors is discussed although epidemiological studies are contradictory. Therapeutics are primarily based on hormonal treatments but better understanding of pathophysiology should allow targeted non-hormonal therapy. The clinical examination is sometimes negative, which should not eliminate the diagnosis and imposes complementary examinations as best as possible by referents.
PMID: 29150232 [PubMed - as supplied by publisher]

Source: Presse Medicale - November 14, 2017 Category: General Medicine Authors: Daraï E, Ploteau S, Ballester M, Bendifallah S Tags: Presse Med Source Type: research