Impaired Left Atrial Strain as a Predictor of New-onset Atrial Fibrillation After Aortic Valve Replacement Independently of Left Atrial Size

Conclusions In severe aortic stenosis, left atrial dysfunction predicted the incidence of postoperative AF independently of left atrial dilation, suggesting that speckle-tracking echocardiography before surgery may help in risk stratification, particularly in patients with nondilated left atria.
Source: Revista Espanola de Cardiologia - Category: Cardiology Source Type: research

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Transcatheter aortic valve replacement (TAVR) has been increasingly utilized as an intervention for the management of symptomatic intermediate and high risk severe aortic stenosis, and utilization rates are expected to increase exponentially worldwide.1,2 One of the most frequent complication of TAVR is the development of New-onset Atrial Fibrillation (NOAF), with an estimated incidence ranging from 16% to 51.1%.3 NOAF corresponds to the detection of atrial fibrillation (AF) during or after the TAVR procedure in a patient without previously known AF.
Source: Heart and Lung - Category: Intensive Care Authors: Source Type: research
AbstractBackgroundThe aim of this retrospective study was to determine changes in outcomes after surgical aortic valve replacement (SAVR) for aortic stenosis (AS) in Iceland over a 15 ‐year period.MethodsWe included 587 patients who underwent SAVR for AS in Iceland during the period 2002 ‐2016, with a total follow‐up of 3245 patient‐years. Short‐term and long‐term outcomes, 30‐day mortality, and long‐term survival (Kaplan–Meier) were analyzed. Univariate linear regression and univariate and multinomial logistic regression analyses were performed on preoperative and p erioperative variables. Poisson re...
Source: Journal of Cardiac Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: ORIGINAL ARTICLE Source Type: research
CONCLUSION: In this study, we could not detect an advantage in survival when SAVR or TAVR were utilized in intermediate to high surgical risk patients needing aortic valve replacement for severe aortic stenosis. PMID: 31596707 [PubMed - in process]
Source: The Heart Surgery Forum - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Heart Surg Forum Source Type: research
Conclusions: TAVR is comparable to SAVR in terms of mortality and disabling stroke in severe AS patients at low and intermediate risk, but higher proportion of AV re-intervention observed in TAVR. Those results should encourage caution when extending the indications of TAVR into low risk patients, especially for young low risk patients. Systematic review registration: PROSPERO CRD 42018112626. PMID: 31285888 [PubMed]
Source: Journal of Thoracic Disease - Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research
Abstract BACKGROUND: The purpose of this study was to investigate if the transcatheter aortic valve replacement (TAVR) risk score can independently predict outcomes following TAVR, and to evaluate its predictive performance.Methods and Results:This retrospective multicenter study comprised 682 patients with severe aortic stenosis who underwent TAVR. The primary endpoint was all-cause death following TAVR. The clinical model was established using variables identified as independent predictors in the multivariate analysis. Incremental values were assessed after adding atrial fibrillation, body mass index (BMI), ...
Source: Circulation Journal - Category: Cardiology Authors: Tags: Circ J Source Type: research
Conclusions: Over a 10-year period, incidentally detected cardiac amyloidosis occurred in 0.2% of the mitral valve surgical cases. The outcomes for these patients undergoing mitral valve surgery were excellent, with no complications or deaths attributable to surgery at a mean follow-up of 1,023 days.Cardiology
Source: Cardiology - Category: Cardiology Source Type: research
A 81-year-old male patient with chronic obstructive lung disease, decompensated severe calcified aortic stenosis, moderately to severely reduced biventricular systolic function, and atrial fibrillation with secondary pulmonary hypertension was referred to our institution. He was treated with diuretics, oral anticoagulants followed by low dose beta blocker. After cardiac recompensation coronary artery disease was excluded by coronary angiogram. Computed tomography (CT) angiography was performed prior to transcatheter aortic valve replacement (TAVR). Unexpectedly, CT (Panel C) and transthoracic echocardiography without contr...
Source: European Heart Journal - Category: Cardiology Source Type: research
ConclusionsRelative to transfemoral TAVR, patients undergoing transapical TAVR are at increased risk for new-onset bundle branch block, peri-procedural myocardial infarction, rehospitalization, TAV-in-TAV deployment, and all-cause mortality at 1  year. Interventional cardiologists and cardiothoracic surgeons alike should take these findings into consideration when choosing which approach is most suitable for patients undergoing TAVR for severe aortic stenosis.
Source: Cardiology and Therapy - Category: Cardiology Source Type: research
Publication date: Available online 19 May 2019Source: Revista Portuguesa de Cardiologia (English Edition)Author(s): Dina Bento, Pedro Coelho, João Lopes, José FragataAbstractIntroductionAortic stenosis (AS) is the most common valvular disease in the elderly, affecting around 8.1% by the age of 85, with a negative impact on quality of life.ObjectiveTo determine the impact of surgical aortic valve replacement (AVR) on octogenarian quality of life in octogenarians.MethodsIn a single-center retrospective study of octogenarians undergoing isolated SAVR for symptomatic AS between 2011 and 2015, quality of life was ...
Source: Revista Portuguesa de Cardiologia - Category: Cardiology Source Type: research
AbstractWarfarin, a vitamin K antagonist, is the most common anticoagulant used to prevent thromboembolisms associated with atrial fibrillation or following valvular surgery. Although several studies have revealed that long-term warfarin use accelerates aortic valve calcification and the development of aortic stenosis (AS), the detailed mechanism for this phenomenon remains unclear. Therefore, our aim was twofold: to establish the conditions for warfarin-induced calcification of human aortic valve interstitial cells (HAVICs) using high-inorganic phosphate (Pi) conditions and to investigate the underlying mechanism. We prep...
Source: Journal of Bone and Mineral Metabolism - Category: Orthopaedics Source Type: research
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