Human pegivirus (HPgV) infection in sub ‐Saharan Africa—A call for a renewed research agenda

Summary The human pegivirus (HPgV)—formerly GB virus C—has a beneficial impact on HIV disease progression that has been described in multiple studies. Given the high prevalence of HIV in sub‐Saharan Africa and the continuing need to suppress HIV replication, this review provides a comprehensive overview of the existing data on HPgV infection in sub‐Saharan Africa, with a particular focus on studies of prevalence and the circulating HPgV genotypes. This review also highlights the need for additional studies of HPgV conducted on the African continent and proposes a research agenda for evaluation of HPgV.
Source: Reviews in Medical Virology - Category: Virology Authors: Tags: REVIEW Source Type: research