When Does Atypical Ductal Hyperplasia Require Surgical Excision?

When Does Atypical Ductal Hyperplasia Require Surgical Excision? Surg Oncol Clin N Am. 2018 Jan;27(1):23-32 Authors: Racz JM, Degnim AC Abstract Atypical ductal hyperplasia (ADH) is a proliferative, nonobligate precursor breast lesion and a marker of increased risk for breast carcinoma. Surgical excision remains the standard recommendation following a core needle biopsy result consistent with ADH. Recent research suggests that women with no mass lesion or discordance, removal of greater than or equal to 90% of calcifications at the time of core needle biopsy, involvement of less than or equal to 2 terminal duct lobular units, and absence of cytologic atypia or necrosis are likely to have a less than 5% chance of a missed cancer. PMID: 29132563 [PubMed - in process]
Source: Clinical Breast Cancer - Category: Cancer & Oncology Authors: Tags: Surg Oncol Clin N Am Source Type: research