Anatomy and Breast Cancer Staging: Is It Still Relevant?

Anatomy and Breast Cancer Staging: Is It Still Relevant? Surg Oncol Clin N Am. 2018 Jan;27(1):51-67 Authors: Plichta JK, Campbell BM, Mittendorf EA, Hwang ES Abstract Breast cancer staging concisely summarizes disease status, creating a framework for assessing and relaying prognostic information. The fundamental concepts and components of breast cancer staging are reviewed. The AJCC Cancer Staging Manual, which includes traditional anatomic factors, now includes additional tumor characteristics: tumor grade, estrogen receptor status, progesterone receptor status, human epidermal growth factor receptor 2 status, and (when available) multigene panel testing from the primary tumor. With these updates, staging provides the most reliable system for accurately predicting patient outcome. When the AJCC 8th edition guidelines are adopted, they will more closely reflect tumor biology. PMID: 29132565 [PubMed - in process]
Source: Clinical Breast Cancer - Category: Cancer & Oncology Authors: Tags: Surg Oncol Clin N Am Source Type: research