New York Times (NYT) article looks at OA risk after knee ligament tear and ACL reconstruction

An article in The New York Times (NYT) discusses anterior cruciate ligament (ACL) repair and an increased likelihood of developing osteoarthritis (OA).
Source: Orthogate - Latest News - Category: Orthopaedics Tags: Featured Editors Choice News Source Type: news

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AbstractPurposeThe aim of this review was to compare the clinical outcomes of anterior cruciate ligament reconstruction (ACLR) with either meniscal repair or meniscectomy for concomitant meniscal injury. The primary hypothesis was that short-term clinical outcomes ( ≤ 2-year follow-up) for ACLR concomitant with either meniscal repair or resection would be similar. The secondary hypothesis was that ACLR with meniscal repair would result in better longer term outcomes compared with meniscal resection.MethodsThe authors searched two online databases (EMBASE and MEDLINE) from inception until March 2018 for the litera...
Source: Knee Surgery, Sports Traumatology, Arthroscopy - Category: Orthopaedics Source Type: research
The prevalence of osteoarthritis following failed meniscal repair has been shown to be significantly increased when compared to successful repair. The aim of this study was to determine whether the addition of anterolateral ligament reconstruction (ALLR) and consequent improved rotational knee stability confers a protective effect on medial meniscal repairs performed at the time of anterior cruciate ligament reconstruction (ACLR).
Source: Arthroscopy - Journal of Arthroscopic and Related Surgery - Category: Surgery Authors: Source Type: research
Authors: Verhelst PJ, Luyckx T Abstract The rupture of the anterior cruciate ligament is one of the most common orthopaedic injuries. This review gives an overview of the surgical treatment of the ACL rupture. A correct knowledge of the anatomy of the ACL is crucial in treating this injury. Recent studies describe the ACl as flat rather than divided in distinct structural bundles. Reconstructive and primary repair techniques can be used to approach this native anatomy. Reconstructive surgery of the ACL still is the golden standard in ACL surgery. An individualized approach is key and should be used. However, ACL re...
Source: Acta Orthopaedica Belgica - Category: Orthopaedics Tags: Acta Orthop Belg Source Type: research
AbstractPurpose of ReviewThis review evaluates current clinical literature on the use of platelet-rich plasma (PRP), including leukocyte-rich PRP (LR-PRP) and leukocyte-poor PRP (LP-PRP), in order to develop evidence-based recommendations for various musculoskeletal indications.Recent FindingsAbundant high-quality evidence supports the use of LR-PRP injection for lateral epicondylitis and LP-PRP for osteoarthritis of the knee. Moderate high-quality evidence supports the use of LR-PRP injection for patellar tendinopathy and of PRP injection for plantar fasciitis and donor site pain in patellar tendon graft BTB ACL reconstru...
Source: Current Reviews in Musculoskeletal Medicine - Category: Orthopaedics Source Type: research
Publication date: Available online 30 July 2018Source: Arthroscopy TechniquesAuthor(s): Colin M. Robbins, Colin P. Murphy, Blake T. Daney, Anthony Sanchez, Matthew T. ProvencherAbstractIn recent years there has been increased attention on preserving the menisci because they perform vital roles in maintaining knee joint homeostasis. The anterolateral (AL) meniscal root is particularly vulnerable during anterior cruciate ligament reconstruction. When the AL root is iatrogenically injured, it is imperative that it is repaired in a timely fashion to prevent early-onset osteoarthritis. In this article we outline our knotless su...
Source: Arthroscopy Techniques - Category: Surgery Source Type: research
ConclusionMeniscus resection in addition to ACL reconstruction resulted in worse clinical outcomes than isolated ACL reconstruction patients; a result not seen within the meniscus repair group. This suggests that, when possible, meniscus repair may provide greater clinical outcomes over resection when treating a reparable meniscal tear that presents along with an ACL tear. Clinicians should consider and implement these findings for the management of future meniscus tear patients within their clinical practice.Level of evidenceLevel III.
Source: Knee Surgery, Sports Traumatology, Arthroscopy - Category: Orthopaedics Source Type: research
J Knee Surg DOI: 10.1055/s-0038-1655765The purpose of this study was to assess intra-articular use of a nonabsorbable braided suture tape for its biocompatibility when implanted adjacent to the native anterior cruciate ligament (ACL) in a canine model. Establishing biocompatibility of suture tape in the knee is an important foundational step for clinicians considering use of suture tape augmentation for ACL reconstruction or repair. The study hypothesis was that a nonabsorbable braided suture tape would be biocompatible in the knee with no resultant adverse functional consequences, and no significant intra-articular synovi...
Source: Journal of Knee Surgery - Category: Orthopaedics Authors: Tags: Original Article Source Type: research
ABSTRACT To determine the transcriptional profile of synovium during the molecular phase of post‐traumatic osteoarthritis, anterior cruciate ligament transections (ACL) were performed in 36 Yucatan minipigs. Equal numbers were randomly assigned to no further treatment, ACL reconstruction or repair. Perimeniscal synovium for histopathology and RNA‐sequencing was harvested at 1 and 4 weeks post‐operatively and from 6 healthy control animals. Microscopic synovitis scores significantly worsened at 1 (p 
Source: Journal of Orthopaedic Research - Category: Orthopaedics Authors: Tags: Research Article Source Type: research
AbstractPurposeTo compare patient reported outcome measures (PROMs) during the first postoperative year between isolated anterior cruciate ligament (ACL) reconstruction and ACL reconstruction with concomitant meniscal intervention.MethodsPatients who underwent primary ACL reconstruction at Capio Artro Clinic, Stockholm, Sweden, between 1st Jan 2001 and 31st Dec 2014 without concomitant injuries others than meniscal and/or cartilage lesions were included. Five groups of meniscal treatment simultaneously to ACL reconstruction were established; medial meniscal (MM) resection, MM repair, lateral meniscal (LM) resection, LM rep...
Source: Knee Surgery, Sports Traumatology, Arthroscopy - Category: Orthopaedics Source Type: research
This study confirmed the development of a microscopic PTOA stage after ACL surgery in the porcine model. Upregulation of multiple proteases (including MMP1 and ADAMTS4) were found; however, the level of expression remained orders of magnitude below that of extracellular matrix protein‐coding genes (including COL2A1 and ACAN). Clinical significance: Genes with established role in PTOA as well as novel targets for specific intervention were identified. This article is protected by copyright. All rights reserved
Source: Journal of Orthopaedic Research - Category: Orthopaedics Authors: Tags: Research Article Source Type: research
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