Morphological and immunohistochemical features of pulmonary vasculopathy in end-stage left ventricular systolic failure

Eligibility for heart transplantation in end-stage left heart disease can be affected by the development of pulmonary vasculopathy. This can lead to pulmonary hypertension ([PH]- group-2), which is recognized as a factor of poor prognosis. Literature data regarding pathophysiology and morphology of the pulmonary vascular lesions are scarce in this group of patients.1,2 Additionally, it has been hypothesized that elevation of the pulmonary arterial pressure in the context of left ventricular failure depends on the integrity and functional capacity of the right ventricle.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Source Type: research