Finding a key to unlock blocked differentiation in microRNA-deficient embryonic stem cells

(University of Alabama at Birmingham) In a study published in Stem Cell Reports, Rui Zhao and colleagues have partly solved a long-unanswered basic question about stem cells -- why are pluripotent stem cells that have mutations to block the production of microRNAs unable to differentiate?
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news