Ginsenoside Rb1 improves leptin sensitivity in the prefrontal cortex in obese mice.
CONCLUSION: These results indicate that Rb1 reverses central leptin resistance and improves leptin-BDNF-neurite outgrowth and synaptogenesis in the prefrontal cortical neurons. Thus, Rb1 supplementation may be a beneficial avenue to treat obesity-associated neurodegenerative disorders.
PMID: 29130652 [PubMed - as supplied by publisher]
Source: CNS Neuroscience and Therapeutics - Category: Neuroscience Authors: Wu Y, Huang XF, Bell C, Yu Y Tags: CNS Neurosci Ther Source Type: research
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