STRC Deletion is a Frequent Cause of Slight to Moderate Congenital Hearing Impairment in the Czech Republic
Conclusions: Following GJB2, STRC was the second most frequently mutated gene in patients from the Czech Republic with hearing loss. To decrease the cost of testing, we recommend STRC deletion screening with MLPA before next-generation sequencing. The existence of a pseudogene and polymorphic STRC regions can lead to false-positive or false-negative results when copy number variation analysis is based on next-generation sequencing data.
This study aims to explore the efficacy and long-term effects of acupuncture in patients with ISSNHL. This study will be a randomized controlled trial with strict methodology and few design deficits. If our study yields positive results, acupuncture could be recommended as a salvage therapy for patients with ISSNHL.Trial registrationChinese Clinical Trial Registry,ChiCTR-ICR-15006787. Registered on 12 July 2015.
New research suggests that mindfulness-based cognitive therapy relieves the severity of tinnitus considerably, compared with other relaxation techniques.
Condition: Tinnitus, Subjective Intervention: Device: Transcranial electrical stimulation (tES) Sponsors: Northwestern University; National Institute on Deafness and Other Communication Disorders (NIDCD) Not yet recruiting
Authors: Hempel JM, Simon F, Müller JM Abstract The indications for cochlear implantation (CI) have expanded over the last few years. There is evidence that some adult patients with pre- or perilingual onset of deafness may gain from implantation. Similarly, CI in patients with single-sided deafness may offer significant benefits in terms of quality of life and social as well as academic development. In this setting, directional hearing may be restored and speech comprehension, especially in noise, may be optimized. In patients with intractable tinnitus and profound hearing loss, CI not only improves speech pe...
Listening to loud music at a concert can cause ringing in the ears, which is known as tinnitus. Learn how to stop the ringing and prevent it in the future.
Jae-Jin Song, Kyungsoo Kim, Woongsang Sunwoo, Griet Mertens, Paul Van de Heyning, Dirk De Ridder, Sven Vanneste, Sang-Youp Lee, Kyung-Joon Park, Hongsoo Choi, Ji-Woong Choi