A prospective evaluation of hippocampal radiation dose volume effects and memory deficits following cranial irradiation.

CONCLUSIONS: This prospective study demonstrates an association between hippocampal dose volume effects and memory decline measured by HVLT-R DR over a wide dose range. These data support a potential benefit of hippocampal sparing and encourage continued trial enrollment. PMID: 29128167 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29128167?dopt=Abstract

Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - November 8, 2017 Category: Radiology Authors: Ma TM, Grimm J, McIntyre R, Anderson-Keightly H, Kleinberg LR, Hales RK, Moore J, Vannorsdall T, Redmond KJ Tags: Radiother Oncol Source Type: research