Environmental adversities and psychotic symptoms: The impact of timing of trauma, abuse, and neglect

Trauma and adverse childhood experiences (ACE) occur more often in mental illness, including psychosis, than in the general population. Individuals with psychosis (cases) report a higher number and severity (dose) of adversities than healthy controls. While a dose-dependent increase of adversities has been related to more severe psychopathology, the role of type and timing is still insufficiently understood on the exacerbation of positive and negative psychotic symptoms. Moreover, dissociative symptoms were examined as potential mediator between adversities and severity of psychotic symptoms.

Source: Schizophrenia Research - November 13, 2017 Category: Psychiatry Authors: Inga Schalinski, Susanne Breinlinger, Vanessa Hirt, Martin H. Teicher, Michael Odenwald, Brigitte Rockstroh Source Type: research