Associations between asymmetric dimethylarginine (ADMA), nitrite-dependent renal carbonic anhydrase activity and plasma testosterone levels in hypogonadal men.

CONCLUSIONS: Impaired testosterone synthesis in hypogonadal men favors inflammatory processes, elevates inducible NOS-mediated NO formation, and impairs CA-dependent nitrite reabsorption. Normalization of plasma testosterone reverses these processes. Pharmacological testosterone may combat atherosclerosis in hypogonadal hypogonadism. PMID: 29128547 [PubMed - as supplied by publisher]
Source: Hellenic Journal of Cardiology - Category: Cardiology Tags: Hellenic J Cardiol Source Type: research