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Soluble Interleukin 2 Receptor IDs Sarcoidosis in Uveitis

sIL - 2R has slightly better diagnostic value than ACE for sarcoidosis in patients with uveitis
Source: Pulmonary Medicine News - Doctors Lounge - Category: Respiratory Medicine Tags: Internal Medicine, Emergency Medicine, Ophthalmology, Pathology, Pulmonology, Rheumatology, Journal, Source Type: news

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This study investigated the effects of an exercise program on functional capacity and quality of life in patients with stage 3 and stage 4 sarcoidosis. Methods: Eighteen patients with stage 3 and 4 sarcoidosis were recruited; 9 received 12 wk of supervised exercise training and 9 received usual care. Patients underwent the following evaluations at baseline and follow-up: 6-min walk test, maximal inspiratory and expiratory pressure tests, back and leg dynamometer test, modified Medical Research Council Dyspnea Scale, Fatigue Severity Scale, St George Respiratory Questionnaire, Short Form-36 Quality of Life Questionnaire,...
Source: Journal of Cardiopulmonary Rehabilitation - Category: Rehabilitation Tags: Pulmonary Rehabilitation Source Type: research
• Heart transplantation for cardiac sarcoidosis is increasing• Mechanical support as bridge to transplant is an option in cardiac sarcoid• Post-transplant outcomes are favorable in cardiac sarcoid patients
Source: Journal of Cardiac Failure - Category: Cardiology Authors: Tags: Clinical Investigation Source Type: research
AbstractThe original version of abstract PO-162 “Chronic Granulomatous Disease in a Brazilian Patient Mimetizing Sarcoidosis” incorrectly listed the name of the second author as Micheli Barsioti. The correct spelling of the author’s name is Michele Baziotti Man.
Source: Journal of Clinical Immunology - Category: Allergy & Immunology Source Type: research
Clinical and radiological manifestations of tuberculosis (TB) are heterogeneous and differential diagnosis can include both benign and malignant diseases (e.g., sarcoidosis, metastatic diseases, and lymphoma). Diagnostic dilemmas can delay appropriate therapy, favoring Mycobacterium tuberculosis transmission.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Medical Imagery Source Type: research
We describe the second reported case of GLILD in a patient with 22q11.2 deletion syndrome (22q11.2DS) and review the recent literature surrounding GLILD.Recent FindingsGLILD is characterized by granulomata and lymphoproliferation. Consensus statements and retrospective and case-control studies have better elucidated the clinicopathological and radiographic manifestations of GLILD, allowing for its differentiation from similar conditions like sarcoidosis. Gaps of knowledge remain, however, particularly regarding optimal management strategies. Combination therapies targeting T and B cell populations have recently shown favor...
Source: Current Allergy and Asthma Reports - Category: Allergy & Immunology Source Type: research
In this issue of Journal of Neuro-Ophthalmology, M. Tariq Bhatti, MD and Mark L. Moster, MD will discuss the following 6 articles: Nachev P, Rose GE, Verity DH, Manohar SG, MacKenzie K, Adams G, Theodorou M, Pankhurst QA, Kennard C. Magnetic oculomotor prosthetics for acquired nystagmus. Ophthalmology. 2017;124:1556–1564.Vestergaard N, Rosenberg T, Torp-Pedersen C, Vorum H, Andersen CU, Aasbjerg K. Increased mortality and comorbidity associated with Leber's hereditary optic neuropathy: a nationwide cohort study. Invest Ophthalmol Vis Sci. 2017;58:4586–4592.Roberts DR, Albrecht MH, Collins HR, Asemani D, Chatte...
Source: Journal of Neuro-Ophthalmology - Category: Opthalmology Tags: Literature Commentary: PDF Only Source Type: research
We aimed to investigate sarcoidosis mortality in a large, population-based cohort, taking into account disease heterogeneity. Individuals with incident sarcoidosis (n=8207) were identified from the Swedish National Patient Register using International Classification of Disease codes (2003-2013). In a subset, cases receiving treatment ±3 months from diagnosis were identified from the Prescribed Drug Register. Nonsarcoidosis comparators from the general population were matched to cases 10:1 on birth year, sex and county. Individuals were followed for all-cause death in the Cause of Death Register. Adjusted mortal...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Interstitial and orphan lung disease Original Articles: Interstitial lung disease Source Type: research
AbstractPurpose of ReviewCardiac involvement is increasingly being recognized as a cause of significant morbidity and mortality in patients with sarcoidosis. Unfortunately, imaging cardiac sarcoidosis (CS) remains a challenge and often relies on advanced imaging modalities. The aim of this review is to provide an up-to-date overview of the role of molecular imaging for the diagnosis of cardiac sarcoidosis, with particular emphasis on the use of FDG and non-FDG PET.Recent FindingsIn the last few years, FDG-PET has established itself as an accurate imaging study for the assessment of CS. New diagnostic criteria have recently...
Source: Current Cardiovascular Imaging Reports - Category: Radiology Source Type: research
im KB Abstract Sarcoidosis is characterised by granulomatous inflammation in one or more organs, including the heart. Cardiac sarcoidosis generally has non-specific symptoms, and the disease is often diagnosed at a late stage. The condition is associated with cardiomyopathy and arrhythmia and may be fatal. PMID: 29460602 [PubMed - as supplied by publisher]
Source: Tidsskrift for den Norske Laegeforening - Category: General Medicine Authors: Tags: Tidsskr Nor Laegeforen Source Type: research
Infliximab, a monoclonal antibody against tumor necrosis factor alpha (TNF- α) is effective third-line therapy in severe sarcoidosis. The originator product of Infliximab, Remicade®, is expensive, limiting universal access. Recently, a less expensive biosimilar of infliximab, Inflectra®, has become available, but the efficacy and tolerability has not been studied in sarc oidosis.
Source: Respiratory Medicine - Category: Respiratory Medicine Authors: Source Type: research
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