World Antibiotic Awareness Week

Professor Dame Sally Davies, England's Chief Medical Officer, recently warned that the world could face a  " post-antibiotic apocalypse.” She urged that, unless action is taken to halt the practices that have allowed antibiotic resistance to spread and ways are found to develop new types of antibiotics, we could return to the days when simple wounds, infections or routine operations, are life-threatening. To mark   World Antibiotic Awareness Week, 13th-19th November,  we are highlighting Cochrane  evidence which supports decision-making in the appropriate use of antibiotics. Press Release:Shared decision making and antibiotic use for acute respiratory  infections in primary care (read in Spanish).Improving antibiotic prescribing  in hospitalAntibiotics for preventing recurrent sore throatAntibiotics for sore throatTesting blood procalcitonin levels to decide when to start and stop antibiotics in adults with acute respiratory tract infections Biomarkers as point-of-care tests to guide antibiotic use for acute respiratory infections Antibiotics for acute otitis media in children Antibiotics for glue earRapid antigen detection tests (RADTs) for group A streptococcus (GAS) in children with pharyngitisAntibiotics for operative vaginal delivery?Antibiotics for episiotomy repair?Antibiotic prophylaxis for women having cesarean sectionTiming of IV prophylactic antibiotics for women having caesarean deliv...
Source: Cochrane News and Events - Category: Information Technology Authors: Source Type: news

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AbstractPathological examination of a suckling male lamb showed severe viral pneumonia with suspected bacterial superinfection. Adenovirus was detected by immunohistochemical examination of the affected lung samples. Detection of the suspected adenovirus by PCR and subsequent isolation of the virus were successful. Using next-generation sequencing, the full genome of this ovine adenovirus was sequenced and analysed. A genome sequence comparison showed that it was a novel mastadenovirus type (named “ovine adenovirus 8”) that did not belong to any of the established adenovirus species. The genome is 36,206 bp lon...
Source: Archives of Virology - Category: Virology Source Type: research
In this study, two novel phages (ISF3 and ISF6) of a methylotrophicRaoultella strain were isolated from sewage. To characterize the isolated phages, morphological features, protein profiles, restriction digestion patterns, and partial genome sequences were studied. Despite morphological differences, electron microscopy revealed that both phages had an icosahedral capsid connected to a contractile tail, suggesting that ISF3 and ISF6 both belong to the familyMyoviridae. Partial nucleotide sequences of the ISF3 genome showed 99% to 100% identity to DNA ofKlebsiella pneumonia phages KP15, KP27 and BMBT1; however, the restricti...
Source: Archives of Virology - Category: Virology Source Type: research
Publication date: November 2019Source: Language &Communication, Volume 69Author(s): Jorge Soto-Almela, Gema Alcaraz-MármolAbstractThis paper explores the discursive representation of refugees in a 1.8-million-word corpus of Spanish news articles collected from the digital libraries of El Mundo and El País. Through a corpus-assisted methodology, synchronic and diachronic analyses have been conducted in order to examine the semantic preference of the lemma refugiado over the 2010–16 period. The results show a semantic preference of refugiado for two major semantic sets, namely victimization and dehuma...
Source: Language and Communication - Category: Speech-Language Pathology Source Type: research
ConclusionWe conclude that diaphragm interventions are an essential part of CRS. They are associated with increased perioperative morbidity. This morbidity is not attributable to whether the patient underwent diaphragm stripping or resection. However in mesothelioma and LAMNs, requiring diaphragm resection is likely to be an indicator for tumor aggression.
Source: The American Journal of Surgery - Category: Surgery Source Type: research
Publication date: Available online 24 June 2019Source: Respiratory InvestigationAuthor(s): Tomoo Kishaba
Source: Respiratory Investigation - Category: Respiratory Medicine Source Type: research
Conditions:   Pneumonia;   Mechanical Ventilation Complication Intervention:   Diagnostic Test: taqman array card Sponsors:   Cambridge University Hospitals NHS Foundation Trust;   University of Cambridge;   Public Health England Recruiting
Source: - Category: Research Source Type: clinical trials
The authors of this open access paper review the aging of the kidney and consider the prospects for using factors from young blood as a means of rejuvenation. This is a fairly narrow view, as there are many other approaches that should produce rejuvenation of the aged kidney, ranging from those close to realization, such as senolytic therapies to clear senescent cells, or various approaches to stem cell therapy, to those yet to be achieved, meaning much of the rest of the SENS agenda of rejuvenation biotechnologies to repair the damage that causes aging. Nonetheless, after so many years of trying to persuade the research c...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
It is well known that the most commonly available forms of stem cell therapy produce benefits via signaling on the part of the transplanted cells, which soon die, rather than via any sort of integration of these cells into tissues. These treatments use varieties of what are called mesenchymal stem cells, which is actually a poorly defined, broad category. One clinic's mesenchymal stem cells are usually meaningfully different from those of the next. Nonetheless, these therapies fairly reliably reduce chronic inflammation. This can allow for improved regeneration in patients, but that outcome is much less reliable in practic...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
Six months ago, the Spanish capital set an example creating one of the most ambitious low-emission schemes among European capitals, called Madrid Central. Now, the conservative new mayor wants to roll back the initiative, provoking outrage among civil society and environmental groups...
Source: Healthcare News - Category: Pharmaceuticals Authors: Source Type: news
(University of Portsmouth) For the first time, scientists have been able to study how well synthetic bone grafts stand up to the rigors and 'strains' of life, and how quickly they help bone re-grow and repair.
Source: EurekAlert! - Biology - Category: Biology Source Type: news
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