I swear they make this stuff up!

The latest breast cancer research says that sleeping in a dimly lit, as opposed to dark, room may interfere with how tamoxifen works. Really? They tried it on 12 rats. Yep. So now is news worthy.So now you are supposed to have room darkening shades or convince your local community to turn off the street lights. I'm not buying it. Even if I was still on tamoxifen I would not believe a 12 rat study. This is why they always say more research is needed.Or they just make this stuff up.
Source: Caroline's Breast Cancer Blog - Category: Cancer Tags: cancer research story truth Source Type: blogs

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This study aimed at exploring the role of α-enolase (ENO1) in proliferation, invasion, and cell apoptosis in MDA-MB-231 and MCF-7 breast cancer human cells, to provide a theoretical basis for the clinical treatment of breast cancer. MATERIALS AND METHODS: MDA-MB-231 and MCF-7 cells were randomly divided into five groups: normal control group (Control group), negative control group (negative control virus, NC group), and shENO1 (sh1, sh2, and sh3) group, respectively. The expressions of ENO1 mRNA and protein were measured by Quantitative Real Time-Polymerase Chain Reaction (qRT-PCR) and Western blot, respectively....
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Publication date: Available online 21 January 2020Source: MethodsAuthor(s): Martina Sollini, Luca Cozzi, Gaia Ninatti, Lidija Antunovic, Lara Cavinato, Arturo Chiti, Margarita KirienkoAbstractThe aim of the present review was to assess the current status of positron emission tomography/computed tomography (PET/CT) radiomics research in breast cancer, and in particular to analyze the strengths and weaknesses of the published papers in order to identify challenges and suggest possible solutions and future research directions. Various combinations of the terms “breast”, “radiomic”, “PET”, &...
Source: Methods - Category: Molecular Biology Source Type: research
Publication date: Available online 20 January 2020Source: Process BiochemistryAuthor(s): M. Uzma, N. Sunayana, Vinay B. Raghavendra, C.S. Madhu, Rajasree Shanmuganathan, Kathirvel BrindhadeviAbstractThe current study aimed at developing gold nanoparticles (AuNPs) using the aqueous extract of the medicinal plant Commiphora wightii. The phytosynthesized gold nanoparticles (Cw@AuNPs) were evaluated for their anticancer activity against MCF-7 breast cancer cell model. The formation of AuNPs by Commiphora wightii leaf extract was confirmed by UV–Visible spectra where their surface plasmon resonance was found at 533&thinsp...
Source: Process Biochemistry - Category: Biochemistry Source Type: research
Publication date: Available online 21 January 2020Source: Journal of Electroanalytical ChemistryAuthor(s): Shuang Dong, Zhengyun Wang, Junlei Wang, Muhammad Asif, Yin Yao, Fei Xiao, Hongfang LiuAbstractThe significance of in situ detection of small biomolecules associated with specific cancer diseases have stimulated the design of flexible film electrode materials. In this work, a green and facile strategy was presented to fabricate flexible N,S-reduced graphene oxide film (N,S-rGOF) by respiratory mechanism of sulfate-reducing bacteria (SRB). The used microbial method allows us to fabricate N,S-rGOF under green and mild c...
Source: Journal of Electroanalytical Chemistry - Category: Chemistry Source Type: research
Publication date: Available online 20 January 2020Source: Journal of Photochemistry and Photobiology B: BiologyAuthor(s): Vilius Poderys, Greta Jarockyte, Saulius Bagdonas, Vitalijus Karabanovas, Ricardas RotomskisAbstractSuitable properties as well as eco-friendly synthesis of photoluminescent Au nanoclusters (NCs) make them promising compounds for biomedical diagnostics and visualization applications. However, the potential photochemical activity of such agents on cancerous cells is largely unknown. The nanoclusters (BSA-Au NCs) were synthetized in the presence of BSA (an average hydrodynamic diameter was about 9.4 nm,...
Source: Journal of Photochemistry and Photobiology B: Biology - Category: Speech-Language Pathology Source Type: research
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Source: Health Communication - Category: Health Management Authors: Source Type: research
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Source: Health Communication - Category: Health Management Authors: Source Type: research
Publication date: Available online 20 January 2020Source: Pathology - Research and PracticeAuthor(s): In Hye Song, Sook-Hee Hong, Kyo Yeong Lee, Jun Kang, Sung Hak Lee, Jieun Lee, Ahwon LeeAbstractDevelopment of molecular technology has led to the expansion of next generation sequencing (NGS) in area of diagnostic pathology. Here we present a case in which a lung tumor, which resembled an atypical carcinoid tumor, was revealed as metastatic breast cancer by next generation sequencing. A 50-year-old female, who had received modified radical mastectomy for breast cancer, presented with a 2.1 cm sized lung mass. The ma...
Source: Pathology Research and Practice - Category: Pathology Source Type: research
Publication date: February 2020Source: Journal of Comparative Pathology, Volume 175Author(s): H. Ariyarathna, N. Thomson, D. Aberdein, J.S. MundaySummaryTumour histological classification and grade are frequently used to predict the prognosis of canine mammary gland tumours. While these techniques provide some information about tumour behaviour, it is currently difficult to predict which tumours will metastasize. Mast cell density has been shown to predict metastasis in human breast cancer. The present study investigated whether the average mast cell density in 10 high-power (×400) microscopical fields (10 HPFs), eva...
Source: Journal of Comparative Pathology - Category: Pathology Source Type: research
ConclusionsTaken together, our results suggest that oleandrin induces mitochondrial-mediated apoptosis by activating endoplasmic reticulum stress in breast cancer. Moreover, oleandrin may be an effective strategy for the treatment of breast cancer.Graphical abstract
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
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