Is dose de-escalation possible in sarcoma patients treated with enlarged limb sparing resection?

CONCLUSION: In this retrospective analysis of patients having enlarged surgery and RT, histological subtype is the strongest predictor of LR, whereas dose de-escalation did not lead to worse outcomes. A dose of 50 Gy may be recommended in case of planned enlarged surgery with R0 margins.
PMID: 29126649 [PubMed - as supplied by publisher]

Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - November 7, 2017 Category: Radiology Authors: Levy A, Bonvalot S, Bellefqih S, Terrier P, Le Cesne A, Le Péchoux C Tags: Radiother Oncol Source Type: research