Vitamin D ₃ deficiency and its association with nasal polyposis in patients with cystic fibrosis and patients with chronic rhinosinusitis.

CONCLUSION: VD3 deficiency seemed to be associated with the presence of nasal polyps in the patients with CRS and in the patients with CF in a similar manner. The lower the level of serum VD3, the more severe the mucosal disease was found in the imaging studies and the more frequent microbial colonization of the patients with CF and the patients with CRS. PMID: 29122084 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - Category: ENT & OMF Authors: Tags: Am J Rhinol Allergy Source Type: research

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Publication date: Available online 25 January 2020Source: International Journal of PharmaceuticsAuthor(s): Xue Zheng, Chao Sun, Rilei Yu, Xin Chu, Jiahao Xu, Chengcheng Liu, Miaoqing Zhao, Xuelian Xu, Ming Xia, Cheng WangAbstractRelapse in Allergic Rhinitis (AR) is triggered by various unclear mechanisms. Xanthium strumarium L. as a traditional folk medicine can inhibit inflammatory responses through multiple mechanisms. Xanthatin (XT) is a bioactive compound derived from Xanthium strumarium L, and we developed a polymeric micelle (PM) that is dendritic cells (DCs)-specific targeting delivery system loading XT (NGR-XT-PM) ...
Source: International Journal of Pharmaceutics - Category: Drugs & Pharmacology Source Type: research
Conclusions: Antioxidants that are not specifically targeted to mitochondria fail to accumulate in significant amounts in critical sites of mitochondrial ROS production and may eventually interfere with the ensuing physiological signaling. Mitochondria-targeted antioxidants are more effective, but are expected to interfere with the mitochondrial ROS-dependent physiologic signaling. AA promotes multiple beneficial effects in mitochondria. The complex regulation of vitamin C uptake in these organelles likely contributes to its versatile antioxidant response, thereby providing a central role to the vitamin for adequate contro...
Source: International Journal of Radiation Biology - Category: Radiology Tags: Int J Radiat Biol Source Type: research
Publication date: Available online 9 January 2020Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Federico Lavorini, Celeste Barreto, Job F.M. van Boven, Will Carroll, Joy Conway, Richard W. Costello, Birthe Hellqvist Dahl, Richard P.N. Dekhuijzen, Stephen Holmes, Mark Levy, Mathieu Molimard, Nicholas Roche, Miguel Román-Rodriguez, Nicola Scichilone, Jane Scullion, Omar S. UsmaniSpacers are pressurized metered-dose inhaler (pMDI) accessory devices developed to reduce problems of poor inhaler technique with pMDIs. Spacers that feature a 1-way inspiratory valve are termed valved holding ch...
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Publication date: Available online 25 January 2020Source: Food ChemistryAuthor(s): Gonzalo Cebrero, Oscar Sanhueza, Matías Pezoa, María E. Báez, Jessica Martínez, Mauricio Báez, Edwar FuentesAbstractSome minor constituents of honey samples were determined through a fluorometric-chemical characterization method and related multifactorially with their antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa and with their geographical origin. Rotated principal component analysis identified five significant components in honey: three related to antibacterial activity a...
Source: Food Chemistry - Category: Food Science Source Type: research
In conclusion, although young and non-smoking volunteers considered themselves healthy by questionnaire, 20% showed signs of a heart, liver, or airway disease, and additional 24% were classified as atopics. This suggests that more detailed clinical testing may be necessary to safely exclude those who may adversely react to controlled exposure with sensory irritants. PMID: 31974924 [PubMed - as supplied by publisher]
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Authors: Ashour AS, Dey N, Mohamed WS, Tromp JG, Sherratt RS, Shi F, Moraru L Abstract Wireless Capsule Endoscopy (WCE) is a highly promising technology for gastrointestinal (GI) tract abnormality diagnosis. However, low image resolution and low frame rates are challenging issues in WCE. In addition, the relevant frames containing the features of interest for accurate diagnosis only constitute 1% of the complete video information. For these reasons, analyzing the WCE videos is still a time consuming and laborious examination for the gastroenterologists, which reduces WCE system usability. This leads to the emergent...
Source: Current Medical Imaging Reviews - Category: Radiology Tags: Curr Med Imaging Rev Source Type: research
DiscussionAlthough Retendo® (mucopolygen complex) is commonly used in muscle and tendon diseases, its effect mechanism is not definitely known. But in the light of the findings we acquired in our study, we detected that Retendo® (mucopolygen complex) applied after achilles tendon ruptures positively effected collagen sequencing during recovery in histological terms but didn't have a significant effect on the mean load achilles tendon can tolerate before rupturing.
Source: Journal of Orthopaedics - Category: Orthopaedics Source Type: research
Source: Nutritional Neuroscience - Category: Nutrition Authors: Source Type: research
Authors: Renck AC, Trarbach EB, Frade Costa EM PMID: 31976827 [PubMed - as supplied by publisher]
Source: International Journal for Vitamin and Nutrition Research - Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research
Publication date: Available online 25 January 2020Source: Materials LettersAuthor(s): Yonglin Yu, Bailong Tao, Jinghui Sun, Lingling Liu, Hong ZhengAbstractBacterial-associated infection and poor osseointegration usually led to the failure of titanium (Ti)-based in orthopedic implantation. To solve above issues, a bioactive coating consisted of gelatin (Gel) and chitosan-graft-polyaniline (Chi-PANI) was fabricated with layer-by-layer (LBL) assembly technique on titanium dioxide nanotubes (TNT) substrates. Scanning electron microscopy (SEM), water contact angle (WCA) measurement X-ray photoelectron spectroscopy (XPS) and at...
Source: Materials Letters - Category: Materials Science Source Type: research
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