47. Rate of complications due to non-idiopathic scoliosis spine surgery: The key role of multimodal intraoperative neuromonitoring and mapping

Aim of this study was to evaluate the role of multimodal intraoperative neuromonitoring and mapping (IONM) for detection of intraoperative and postoperative complications in a series of patients with non-idiopathic scoliosis (NI-S).We reviewed IONM records of 32 patients with NI-S (neurofibromatosis, Duchene muscular dystrophy, spinal muscular atrophy, Haberland, Goldenhair, Prader Willi syndrome, mucopolisaccaridosis, tetraparesis, congenital myopathy and neuropathy, achondroplasia, spinal tumor, diastematomyelia) with a mean age at surgery of 14years (range, 6 –25years), who underwent posterior fusion with instrumentation surgery for spinal deformity.
Source: Clinical Neurophysiology - Category: Neuroscience Authors: Source Type: research

Related Links:

Genetics in Medicine, Published online: 14 October 2019; doi:10.1038/s41436-019-0673-0The implementation of newborn screening for spinal muscular atrophy: the Australian experience
Source: Genetics in Medicine - Category: Genetics & Stem Cells Authors: Source Type: research
Authors: Toraih EA, Ameen HM, Hussein MH, Youssef Elabd AA, Mohamed AM, Abdel-Gawad AR, Fawzy MS Abstract Alopecia areata (AA) is a non-scarring hair loss of autoimmune etiology. The autoimmune regulator (AIRE) gene is believed to be an important driver in AA pathogenesis. Genetic variants can alter mRNA expression levels which may provoke an autoimmune response. A total of 337 males (97 AA patients and 240 controls) were enrolled in the current case-control study. On screening of the most frequent variants in the gene, rs2075876 (A/G) polymorphism in intron 5 was selected and genotyped using Real-Time PCR (polymer...
Source: Immunological Investigations - Category: Allergy & Immunology Tags: Immunol Invest Source Type: research
Contributors : Delphine Laustriat ; Jacqueline Gide ; Laetitia Barrault ; Emilie Chautard ; Clara Benoit-Pilven ; Didier Auboeuf ; Anne Boland ; Christophe Battail ; Fran çois Artiguenave ; Jean-François Deleuze ; Paule Bénit ; Pierre Rustin ; Sylvia Franc ; Guillaume Charpentier ; Denis Furling ; Guillaume Bassez ; Xavier Nissan ; Cécile Martinat ; Marc Peschanski ; Sandrine BaghdoyanSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensMajor physiological changes are governed by alternative splicing of RNA, and its misregulation may lead to specific diseases. W...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
Contributors : Kevin I Watt ; Mark Ziemann ; Richard J Mills ; Man-Kit-Sam Lee ; Adam Hagg ; Hongwei Qian ; Fergus L Sully ; Assam El-Osta ; Andrew J Murphy ; Stephen J Tapscott ; James E Hudson ; Paul GregorevicSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensFacioscapulohumeral muscular dystrophy (FSHD) is characterised by a progressive degeneration and weakness of skeletal muscle fibers attributed to inappropriate expression of the transcription factor double homeobox 4 (DUX4). However, the cellular events that precede pathology in DUX4 expressing muscle fibers remain incompletely u...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
This report describes the first case of bilateral sporadic intracochlear schwannomas in a patient with no genetic or clinical features of NF2. PMID: 31598774 [PubMed - as supplied by publisher]
Source: HNO - Category: ENT & OMF Tags: HNO Source Type: research
ConclusionOCI, an important factor to maintain horizontal gaze, was demonstrated to be associated with radiological ASD, suggesting that the occipito-cervical angle influences accelerated cervical degeneration. Since OCI did not change after surgery, degeneration of the cervical spine may be predicted by the value of OCI.NECK trialDutch Trial Register Number NTR1289.PROCON trialTrial Register Number ISRCTN41681847.Graphic abstractThese slides can be retrieved under Electronic Supplementary Material.
Source: European Spine Journal - Category: Orthopaedics Source Type: research
This is the first study to demonstrate that active muscle stiffness with and without the stretch reflex and joint stiffness significantly decreased after repeated stretch ‐shortening cycle exercises, although tendon stiffness measured during ramp and ballistic contractions and neuromuscular activities during the measurement of joint stiffness did not. These results suggested that decline in joint stiffness was related to changes in the active muscle stiffness, but not those in tendon properties or neuromuscular activities. AbstractThe purpose of this study was to elucidate the mechanisms of decline in joint stiffness aft...
Source: Physiological Reports - Category: Physiology Authors: Tags: Original Research Source Type: research
ConclusionMPNST are difficult to manage because of their aggressive nature and the limitations in early diagnosis and management. In patients with Von Recklinghausens disease, malignancy must be suspected when a patient presents with the complaints as mentioned in this case report.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
Conclusions: There is a high complication rate during VEPTR treatment and with final fusion surgery. The stiffness of the spine and thorax allow for only limited correction when performing a final instrumented spondylodesis. Avoiding final fusion may be a viable alternative in case of good coronal and sagittal alignment. Level of Evidence: Level IV—therapeutic.
Source: Journal of Pediatric Orthopaedics - Category: Orthopaedics Tags: Scoliosis Source Type: research
Conclusions: The C-EOS simplifies a complex pathology and the Smith complication classification scheme creates a language to discuss treatment of known complications of growth-friendly spine surgery. Although there is an association between more advanced C-EOS and Smith complications, there does not appear to be a correlation that can satisfy a risk stratification at this time. Level of Evidence: Level II.
Source: Journal of Pediatric Orthopaedics - Category: Orthopaedics Tags: Scoliosis Source Type: research
More News: Back Curves | Brain | Muscular Dystrophy | Neurofibromatosis | Neurology | Neuroscience | Neurosurgery | Prader-Willi Syndrome | Reflex Sympathetic Dystrophy | Scoliosis | Spinal Muscular Atrophy | Study