Facing the threat of antibiotic-resistance: Israel ’s success to prevent and control the spread of carbapenem-resistant bacteria

Facing the threat of antibiotic-resistance: Israel ’s success to prevent and control the spread of carbapenem-resistant bacteria
Source: WHO Feature Stories - Category: International Medicine & Public Health Tags: antimicrobial resistance [subject], European Region [region], Feature [doctype], Israel [country] Source Type: news

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Anand Manoharan, Ranjith JayaramanIndian Journal of Medical Microbiology 2018 36(4):465-474Streptococcus pneumoniae continues to take a heavy toll on childhood mortality and morbidity across the developing world. An estimated 10.6 million invasive pneumococcal diseases (IPDs) occur every year, with nearly 1 million deaths in children under 5 years of age. Introduction of vaccines in the childhood immunisation programme in developed world has brought down the incidence of the disease considerably. However, childhood immunocompromising illnesses including HIV have increased the risk of IPD several folds. There is also a grow...
Source: Indian Journal of Medical Microbiology - Category: Microbiology Authors: Source Type: research
ika Wujec Biofilm, naturally formed by microorganisms as integrated surface-bound communities, is one of the reasons for the development of antimicrobial resistance. Haemophilus spp. are common and representative opportunistic Gram-negative rods forming from the upper respiratory tract microbiota. The aim of this paper was to evaluate the influence of thiazolidine-2,4-dionebased azolidine and chlorophenylthiosemicarbazone hybrids against both planktonic and biofilm-forming Haemophilus spp. cells. The in vitro activity against planktonic and biofilm-forming cells of the tested compounds were evaluated by using the broth...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
ConclusionIsolate KP26 is a hypermucoviscous, multidrug-resistant K. pneumoniae strain that may represent an emerging high-risk clone associated with severe infections in India.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
This study showed that 89.18% of E. coli isolates were multidrug resistant (MDR). Furthermore, MDR extended-spectrum β-lactamases (ESBL)-producing E. coli were detected in the ovaries of four different broiler breeder flocks. Molecular characterization revealed that three isolates harbored blaCTX-M-1 gene and one isolate expressed blaSHV-12 gene. In addition, one blaCTX-M-1 producing E. coli co-harbored the blaTEM-1 gene. These findings would contribute to a better epidemiological understanding of MDR E. coli for improve existing preventive strategies in order to reduce the dissemination of antimicrobial resistance in...
Source: Comparative Immunology, Microbiology and Infectious Diseases - Category: Infectious Diseases Source Type: research
ConclusionNeisseria gonorrhoeae isolates with decreased susceptibility or resistance to ESC have increased over the years. Four major STs with a multidrug-resistant phenotype were identified. These isolates contained a penA mosaic allele or a non-mosaic allele.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
ConclusionsThis study is the first large scale analysis of equine pathogens both by the number of samples and the duration of the study. Our results pointed out the presence of high level of MDR strains and the need to support veterinary antimicrobial stewardship to encourage proper use of antibiotic.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
AbstractBackgroundAntimicrobial resistance (AMR), globally and nationally, is considered as a serious problem. We aimed to assess the knowledge, attitudes, and practices of physicians towards antimicrobial resistance.Aim of the workTo assess the knowledge, attitudes, and practices of physicians towards antimicrobial resistance in Egypt.Study designA cross-sectional study.MethodsThe study was conducted on a group of physicians from various specialties prescribing antibiotics in different hospitals in Fayoum Governorate from January to December 2017. Data was collected using self-administered questionnaires covering four mai...
Source: Journal of Public Health - Category: Health Management Source Type: research
Conclusions The current syndromic management with dual ceftriaxone and azithromycin is due to the high level of azithromycin resistance factually single-drug therapy. High-level tetracycline resistance based on a resistance mechanism other than ribosome protection by the tetM gene product is present in N. gonorrhoeae infecting South African patients.
Source: Sexually Transmitted Diseases - Category: Sexual Medicine Tags: Original Studies Source Type: research
This is the first prevalence study of Mycoplasma genitalium and antimicrobial resistance study in Ireland. In urine samples from men who have sex with men (n = 400) attending a sexually transmitted disease clinic in Dublin, the prevalence of M. genitalium was 3% (12 of 400 specimens; 95% confidence interval, 1.3–4.7%), and the prevalences of macrolide resistance (75%), fluoroquinolone resistance (33.3%), and multidrug resistance (33.3%) were very high.
Source: Sexually Transmitted Diseases - Category: Sexual Medicine Tags: Notes Source Type: research
This study aimed to investigate the prevalence of AMR in household milk for human consumption in Isiolo County, Kenya. The study identified 42 Escherichia coli (E.coli) isolates from 304 milk samples that were collected in randomly selected households in northern Kenya. E. coli was isolated using Eosin Methylene Blue Agar and identified using biochemical tests. The isolates were confirmed using Polymerase Chain Reaction (PCR) and sequencing. The antimicrobial resistance profiles of the isolates to 11 antimicrobial agents were evaluated by disc diffusion method on Mueller Hinton Agar. Additionally, the isolates were evaluat...
Source: Food Control - Category: Food Science Source Type: research
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