Segmentation of the Hippocampus by Transferring Algorithmic Knowledge for large cohort processing

The essential role played by the hippocampus within the human brain makes it a particularly important target for neuroimaging studies. The hippocampus is well known for its functional involvement in the mechanisms of memory and has also been associated with various diseases or conditions through its very structure, either directly in memory-related disorders such as Alzheimer's Disease (Bobinski et al., 1999; Jack et al., 1999; Laakso et al., 1996; Reiman et al., 1998; Schuff et al., 2009; Šimić et al., 1997) and PTSD (Bonne et al., 2001; Gilbertson et al., 2002; Gurvits et al., 1996; Pederson et al., 2004; Shin et al., 2004; but see Landré et al., 2010 for negative results) or indirectly in other disorders such as schizophrenia (Koolschijn and Haren, 2010), obsessive-compulsive di sorder (Boedhoe et al., 2016), depression (Bremner et al., 2000; Janssen et al., 2007; Vythilingam et al., 2002), dementia (Wachinger et al., 2016), and even autism (Aylward et al., 1999; Sparks et al., 2002; but see Piven et al., 1998).
Source: Medical Image Analysis - Category: Radiology Authors: Source Type: research