Very tight versus tight control: which should be the criteria for pharmacologic therapy dose adjustment in diabetes in pregnancy? Evidence from randomized controlled trials

ConclusionsWhen evaluating RCTs which included criteria for pharmacologic GDM therapy dose adjustment, the most common criteria for diagnosis was the two step test, and the most common used therapies were insulin and metformin. Regarding glucose monitoring, the most common frequency was four times per day, fasting and 2 hours after each main meal, using as target glucose values 95mg/dL and 120mg/dL, respectively. Importantly, we found six different criteria for pharmacologic GDM therapy dose adjustment, with the majority using very tight criteria of either 1 or 2 values per week higher than the target values, of which two thirds used only 1 value, and one third 2 values.This article is protected by copyright. All rights reserved.

Source: Acta Obstetricia et Gynecologica Scandinavica - November 10, 2017 Category: OBGYN Authors: Claudia Caissutti, Gabriele Saccone, Andrea Ciardulli, Vincenzo Berghella Tags: Systematic review Source Type: research