Echocardiographic improvements following transsphenoidal surgery for acromegaly
Antonio Ribeiro-Oliveira, Márta Korbonits, Claudia M V FreireNeurology India 2017 65(6):1225-1226
Endocrine Practice, Ahead of Print.
We aimed to determine the long-term effects of Gamma knife radiosurgery (GKS) on remnants in the cavernous sinus (CS) after transsphenoidal surgery (TSS) for acromegaly and to identify its possible adverse effects.
Funding Opportunity PA-18-052 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages R21 applications that propose to conduct secondary analyses of existing data sets relevant to diabetes and selected endocrine and metabolic diseases including thyroid, parathyroid and Cushings diseases and acromegaly; and genetic metabolic disease including cystic fibrosis, lysosomal storage diseases, and disorders of the urea cycle, amino acid metabolism and metal transport where the focus is on peripheral metabolism or organ function; obesity, liver diseases, alimentary GI tract diseases and ...
Conclusion: Reduction in growth hormone levels and insulin-like growth factor type 1 can decrease the LVM and LVMI, which directly or indirectly contributes to the improvement in diastolic as well as systolic function and probably mortality.
Subhash Yadav, Eesh BhatiaNeurology India 2017 65(6):1223-1224
ConclusionsThe results from these long-term placebo-controlled studies confirm the established safety profile of long-acting OCT, in particular low risk of cardiac, hepatic and renal toxicity in a high-risk population.
Conclusion Regarding operated cases of GH-producing pituitary adenoma, acromegaly clinical manifestations tended to be milder at diagnosis in later years of the decade, and acromegaly was diagnosed at lower IGF-1 levels and in smaller lesions. Further study is mandatory for the generalization of this trend.
AbstractPurposeThere is a paucity of epidemiological information on treatment and imaging of pituitary adenomas in Australia.MethodsAustralian data on pituitary surgery, hospital admissions for pituitary adenomas, and pituitary imaging on patients 15 years and over were obtained from administrative databases between 2000/2001 and 2014/2015. Changes over time and by age and sex were assessed.ResultsIn 2014/15 there were 37.7 pituitary procedures/million population, corresponding to a 35.4% (p
In conclusion, although cecal intubation during colonoscopy was successful in all participants, it required a longer time in patients with acromegaly. Our results underscore the importance of and certain technical difficulties involved in colonoscopy procedures in patients with acromegaly, especially in older patients. PMID: 29081443 [PubMed - as supplied by publisher]
Date: Wednesday, 11 29, 2017; Speaker: Andrew Demidowich, MD, Assistant Research Clinician, Office of the Clinical Director, NICHD; Prashant Chittiboina, MD, MPH, Assistant Clinical Investigator,, Neurosurgery Unit for Pituitary and Inheritable Diseases, NINDS; Constantine Stratakis, MD, D(Med)Sc, Scientific Director and, Senior Investigator, Section on Genetics and Endocrinology, NICHD; Building: Building 10 (Clinical Center); Lipsett Amphitheater; CME Credit; Videocast Event