Plasma irisin is elevated in type 2 diabetes and is associated with increased E-selectin levels

Irisin is a hormone released mainly from skeletal muscle after exercise which increases adipose tissue energy expenditure. Adipocytes can also release irisin after exercise, acting as a local adipokine to indu...
Source: Cardiovascular Diabetology - Category: Cardiology Authors: Tags: Original investigation Source Type: research

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This study sought to characterize the changes in general immunity occurring during the progression from pre-diabetes to T2D. Male rats were fed a high-fat high-carbohydrate diet for 20 weeks (pre-diabetes induction period) and kept on the same diet being monitored for a further 12 weeks (experimental period). Blood was collected for haemocytometer analysis on week 0, 4, 8, and 12 of the experimental period after which the animals were sacrificed. Plasma was collected from centrifuged blood for ELISA (TNF-α, CRP, P-selectin, CD40 L, fibrinogen, and IL-6). Blood neutrophils percentage significantly...
Source: Autoimmunity - Category: Allergy & Immunology Tags: Autoimmunity Source Type: research
TYPE 2 diabetes sufferers are advised to cut down on the amount of sugar they consume in order to control the condition. It may seem sensible to replace sugar with sweetener, but artificial sweeteners have also proved somewhat controversial in the health world. So should diabetic people swap sugar for sweetener? One doctor explains.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
CONCLUSIONS: Hybrid procedures are safe and effective both in CLI patients with or without DM, and they should be taken into consideration whenever indications are present. PMID: 30779095 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
AbstractAimTo describe how the group education process for people with type 2 diabetes is experienced by diabetes nurses and dietitians who support the patients ’ learning, in a primary care setting.DesignThe project took place at two primary care settings in the south of Sweden.MethodsData collected from focus ‐group interviews and reflection notes were subjected to phenomenological analysis.ResultsThe specially trained personnel experienced that group education made it possible for the patients to learn through reflection concerning their own and others ’ experiences. Furthermore, group education entailed i...
Source: Nursing Open - Category: Nursing Authors: Tags: RESEARCH ARTICLE Source Type: research
ConclusionIn conclusion, GDM and macrosomia, but not PCOS, are significant risk factors for T2DM in our Lebanese cohort. Our results, reported for the first time in the Middle East, present insights into risk factors management and disease prevention.
Source: Journal of Clinical and Translational Endocrinology - Category: Endocrinology Source Type: research
Hygieia said today that it won 510(k) clearance from the FDA for its insulin management app designed to optimize insulin dosing among people with Type 2 diabetes. The Michigan-based company touted its product as the first insulin management mobile app that can titrate individualized doses for all types of insulin regimens. Get the full story at our sister site, Drug Delivery Business News. The post Hygieia wins FDA clearance for insulin management app appeared first on MassDevice.
Source: Mass Device - Category: Medical Devices Authors: Tags: 510(k) Diabetes Drug-Device Combinations Featured Food & Drug Administration (FDA) mHealth (Mobile Health) Pharmaceuticals Regulatory/Compliance Hygieia Source Type: news
Conditions:   Diabetic Neuropathy Peripheral;   Small Vessel Disease of Diabetes Mellitus;   Vasodilation;   Vasoconstriction Interventions:   Other:  " Rest " ;   Other:  " Exercise " ;   Other:  " Foot  lowering " ;   Other:  " Hyperthermia " Sponsor:   University of Avignon Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Type2 Diabetes Interventions:   Other: Balanced diet high in Slowly Digestible Starch;   Other: Balanced diet low in Slowly Digestible Starch Sponsors:   Mondelēz International, Inc.;   Centre de Recherche en Nutrition Humaine Rhone-Alpe;   Biofortis Mérieux NutriSciences Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Diabetic Neuropathy Peripheral;   Small Vessel Disease of Diabetes Mellitus;   Vasodilation;   Vasoconstriction Interventions:   Other:  " Rest " ;   Other:  " Exercise " ;   Other:  " Foot  lowering " ;   Other:  " Hyperthermia " Sponsor:   University of Avignon Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
  Apollo Endosurgery’s OverStitch device Apollo Endosurgery (NSDQ:APEN) has reported key data from 1,000 patients who underwent endoscopic gastroplasty using the company’s OverStitch device. Published in the journal Gastrointestinal Endoscopy, the data include a mean total weight loss of 14.8%±8.5% at 18 months. Three months following surgery, the impact on obesity-related comorbidities included the complete remission of: 13 of 17 cases of type 2 diabetes. All 28 cases of hypertension. 18 of 32 cases of dyslipidemia. Get the full story on our sister site, Medical Design &Outsourc...
Source: Mass Device - Category: Medical Devices Authors: Tags: Blog Clinical Trials Endoscopic / Arthroscopic News Well Surgical Weight loss Apollo Endosurgery Source Type: news
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