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Effects of hypoglycemia on myocardial susceptibility to ischemia –reperfusion injury and preconditioning in hearts from rats with and without type 2 diabetes

Hypoglycemia is associated with increased mortality rate in patients with diabetes. The underlying mechanisms may involve reduced myocardial tolerance to ischemia and reperfusion (IR) or reduced capacity for i...
Source: Cardiovascular Diabetology - Category: Cardiology Authors: Tags: Original investigation Source Type: research

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ALL food products and restaurant menus should carry compulsory traffic-light labelling to combat Type 2 diabetes, experts say. It would assist the public in making healthier choices and arrest an epidemic that threatens to cripple the NHS, says Diabetes UK.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
TYPE 2 diabetes symptoms include increased thirst and hunger, fatigue and unexplained weight loss. The condition develops later in life, often due to risk factors including being overweight, not exercising regularly or having a poor diet. Dropping this from your diet could reduce your risk of developing the condition.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
TYPE 2 diabetes symptoms include increased thirst and hunger, fatigue and unexplained weight loss. The condition develops later in life, often due to risk factors including being overweight, not exercising regularly or having a poor diet. Dropping this from your diet could reduce your risk of developing the condition.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
In conclusion, the connection between DNA damage and aging is emphasized by the secretion of senescence-associated proteins during cellular senescence, a phenotype which is activated by DNA damage and is common for both human and mice. Though much progress has been achieved, full understanding of these mechanisms has still a long way to go. XPO1 as a Novel Target for Therapies to Enhance Autophagy https://www.fightaging.org/archives/2018/05/xpo1-as-a-novel-target-for-therapies-to-enhance-autophagy/ Autophagy is the name given to a collection of cellular housekeeping processes that recycle damaged and un...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
The 'trendy' diet of intermittent fasting may have adverse consequences on our metabolism, a new study warns. The diet may impair pancreatic function.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Diabetes Type 2 Source Type: news
In this study, a sensitive and efficient UPLC-MS/MS method for the quantification of canagliflozin and its metabolites in rat plasma was established and applied to pharmacokinetics in a type 2 diabetic rat model. We firstly investigated the pharmacokinetic changes of canagliflozin and its metabolites in type 2 diabetic rats in order to use canagliflozin more safely, reasonably and effectively. We identified three types of O-glucuronide metabolites (M5, M7 and M17), two kinds of oxidation metabolites (M8 and M9) and one oxidation and glucuronide metabolite (M16) using API 5600 triple-TOF-MS/MS. Following liquid–li...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
ConclusionsSG seems effective and safe in obese HIV patients. However, ART treatment should be monitored post-SG to control HIV infection. We suggest that some ART should be adapted  before SG conjoints with infectious disease specialists.
Source: Obesity Surgery - Category: Surgery Source Type: research
Health literacy is defined as “the degree to which individuals have the capacity to obtain, process, and understand basic health information and services needed to make appropriate health decisions”[1]. Health numeracy is defined as “the degree to which individuals have the capacity to access, process, interpret, communica te, and act on numerical, quantitative, graphical, bio-statistical, and probabilistic health information needed to make effective health decisions”[2]. Both low health literacy and low health numeracy have been associated with poor health outcomes [3–5].
Source: Patient Education and Counseling - Category: International Medicine & Public Health Authors: Source Type: research
Could some fasting diets increase the risk of type 2 diabetes? That was the question posed by scientists last week, after researchers unveiled evidence that seemed to suggest they might.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
CONCLUSIONS: Decisions on what method to use should be based on considerations of the route of medication administration, the resources available, setting and aim of the assessment. Combining different methods may provide wider insights into adherence and persistence, including patient behaviour. PMID: 29770718 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
More News: Cardiology | Cardiovascular | Diabetes | Diabetes Type 2 | Endocrinology | Heart