Effect of rosuvastatin on fasting and postprandial endothelial biomarker levels and microvascular reactivity in patients with type 2 diabetes and dyslipidemia: a preliminary report

The cardiovascular benefits of statins have been proven, but their effect on circulation in small vessels has not been examined fully. We investigated the effect of 20  mg rosuvastatin on biomarkers, including ...
Source: Cardiovascular Diabetology - Category: Cardiology Authors: Tags: Original investigation Source Type: research

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Those of you following these Wheat Belly and Undoctored Blog posts know that it is no secret that Big Pharma is a predatory, manipulative, cutthroat industry that employs underhanded and unethical tactics as routine business. Part of their huge economic success is that they are so effective in getting my colleagues, mainstream physicians, to drink their Kool-Aid and do a lot of the dirty work for them. Just witness what happened in the opioid crisis—it couldn’t have happened without the willing participation of physicians. It’s no different with “treating” cholesterol, total and LDL, with stat...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: News & Updates cholesterol LDL lipoproteins low-carb small ldl undoctored wheat belly Source Type: blogs
ConclusionAmong patients with knee OA, statin use was associated with radiological worsening over 3 years, regardless of other potential confounding factors (obesity, type 2 diabetes, hypertension, disease duration, symptom intensity and radiological severity).
Source: Joint Bone Spine - Category: Orthopaedics Source Type: research
Publication date: Available online 1 October 2018Source: The Lancet Diabetes &EndocrinologyAuthor(s): Anoop Misra, Naveed Sattar, Nikhil Tandon, Usha Shrivastava, Naval K Vikram, Kamlesh Khunti, Andrew P HillsSummaryCompared with other ethnic groups, south Asian people with type 2 diabetes tend to develop the disease at a younger age and manifest with higher glycaemia, dyslipidaemia, nephropathy, and cardiovascular diseases. Additionally, specific issues that can affect treatment of type 2 diabetes in south Asia include poor awareness of the disease, delay in diagnosis, inadequate treatment, the use of ineffective and ...
Source: The Lancet Diabetes and Endocrinology - Category: Endocrinology Source Type: research
Publication date: Available online 29 September 2018Source: American Heart JournalAuthor(s): Aruna D. Pradhan, Nina P. Paynter, Brendan M. Everett, Robert J. Glynn, Pierre Amarenco, Marshall Elam, Henry Ginsberg, William R. Hiatt, Shun Ishibashi, Wolfgang Koenig, Børge G. Nordestgaard, Jean-Charles Fruchart, Peter Libby, Paul M RidkerAbstractObservational, genetic, and experimental data indicate that triglyceride rich lipoproteins (TRLs) likely participate causally in atherothrombosis. Yet, robust clinical trial evidence that triglyceride (TG) lowering therapy reduces cardiovascular events remains elusive. The selec...
Source: American Heart Journal - Category: Cardiology Source Type: research
Conclusions: Different statins can reduce the risk of cancer in patients with T2DM. Our analyses suggest that rosuvastatin may be more effective than others. PMID: 30254671 [PubMed]
Source: Gastroenterology Research and Practice - Category: Gastroenterology Tags: Gastroenterol Res Pract Source Type: research
Patients with type 2 diabetes given statin or fibrate lipid-lowering therapy have both a reduced risk of developing diabetic retinopathy and being treated for the condition, Japanese claims data show.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news
año JP, Luque RM Abstract Background: Biguanides and statins have been reported to exert beneficial effects on various cancer types. However, their precise effects and underlying molecular mechanisms are still poorly understood. Materials and Methods: We analyzed the relation between metabolic-syndrome, i.e., presence of type-2 diabetes (T2DM), hyperlipidemia and their treatment, with histological, epidemiological, and prognosis variables in two patient cohorts with neuroendocrine-tumors [NETs: lung-carcinoids (LCs; n=81) and gastro-entero-pancreatic (GEP-NET; n=100)]. Additionally, we investigated the...
Source: The Journal of Clinical Endocrinology and Metabolism - Category: Endocrinology Authors: Tags: J Clin Endocrinol Metab Source Type: research
Large doses of an omega-3 fatty acid in fish oil sharply reduced the rate of cardiovascular events in people with a history of heart disease or Type 2 diabetes.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Heart Omega-3 Fatty Acids Diabetes Statins (Cholesterol-Lowering Drugs) Amarin Corp PLC Source Type: news
Large doses of an omega-3 fatty acid in fish oil sharply reduced the rate of cardiovascular events in people with a history of heart disease or Type 2 diabetes.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Heart Omega-3 Fatty Acids Diabetes Statins (Cholesterol-Lowering Drugs) Amarin Corp PLC Source Type: news
Analysis of NHANES data showed no overall benefit of statins for primary prevention, with the exception of adults with type 2 diabetes, and only for those aged 75 to 84 years.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news
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