Prospective validation that subgenual connectivity predicts antidepressant efficacy of transcranial magnetic stimulation sites

The optimal target in the dorsolateral prefrontal cortex (DLPFC) for treating depression with repetitive transcranial magnetic stimulation (rTMS) remains unknown. Better efficacy has been associated with stimulation sites that are 1) more anterior and lateral and 2) more functionally connected to the subgenual cingulate. Here we prospectively test whether these factors predict response in individual patients.

Source: Biological Psychiatry - November 9, 2017 Category: Psychiatry Authors: Anne Weigand, Andreas Horn, Ruth Caballero, Danielle Cooke, Adam P. Stern, Stephan F. Taylor, Daniel Press, Alvaro Pascual-Leone, Michael D. Fox Tags: Archival Report Source Type: research